ID A0A3P8Z869_ESOLU Unreviewed; 1163 AA.
AC A0A3P8Z869;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=PR/SET domain 15 {ECO:0000313|Ensembl:ENSELUP00000024915.1};
GN Name=PRDM15 {ECO:0000313|Ensembl:ENSELUP00000024915.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000024915.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000024915.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000024915.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_010869029.1; XM_010870727.2.
DR AlphaFoldDB; A0A3P8Z869; -.
DR STRING; 8010.ENSELUP00000024915; -.
DR Ensembl; ENSELUT00000036478.2; ENSELUP00000024915.1; ENSELUG00000023702.2.
DR GeneID; 105011004; -.
DR KEGG; els:105011004; -.
DR GeneTree; ENSGT00940000157890; -.
DR InParanoid; A0A3P8Z869; -.
DR OMA; ERGPWAC; -.
DR OrthoDB; 5400229at2759; -.
DR Proteomes; UP000265140; LG07.
DR Bgee; ENSELUG00000023702; Expressed in ovary and 15 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd19199; PR-SET_PRDM15; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 12.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR044409; PRDM15_PR-SET.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24388:SF53; COMBGAP, ISOFORM L-RELATED; 1.
DR PANTHER; PTHR24388; ZINC FINGER PROTEIN; 1.
DR Pfam; PF21549; PRDM2_PR; 1.
DR Pfam; PF00096; zf-C2H2; 8.
DR Pfam; PF13894; zf-C2H2_4; 1.
DR SMART; SM00355; ZnF_C2H2; 17.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 7.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 16.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 14.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 47..157
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 381..403
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 408..436
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 442..460
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 469..491
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 496..523
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 546..573
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 573..600
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 666..693
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 702..729
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 730..757
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 758..785
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 786..813
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 814..841
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 842..870
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 272..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 618..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 919..962
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1123..1163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 928..962
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1139..1163
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1163 AA; 130977 MW; DE81F2A4734F8EE9 CRC64;
MTEQTSDEFI WCEDCRQYHD SECPDLGPVV TVQDSFVLSR ARSSLPESLE IRQVPDGKEG
VFVLQRLVKR TRFGPFEAKR VSHLDKEGLF PLKIFQRDGL VICFDSSNED DCNWMMLVRP
ATEHQHQNLT AYQQDNEVYF NTSQDVLPGS ELRVWYGAFY AKKMERPMLK APVPPPPADV
DASCTKPGLA LGKAGLLLPL VARENDAGGQ GQETSRLVCK VCPAVFVEPQ LLSDHLLSHL
QEVKAVPPCL ETQPQQRDPV EPVTCDDGYG AEPMPAPASP PLVVTKRRPG RPGKRTKGER
KHSGANVASK KKITAPKTVA ATLNMASTDG GESVLEDSGM EIGPDGVAVT MPRVTRTLLS
TGKRGSRKRF LRQGGDHKRV YKCTLCNKIF QNSSNLNRHI RSHGDKLFKC DECDKMFSRK
ESLKQHISYK HSKNEPDIEY RYKCNTCDKA FRVENALKFH NCRTDDKTFQ CEICSRFFST
NSNLSKHKKK HGEKLYACEI CSKMFYRKDV MQDHQRRHTV ANPKQMKREE MEANGEEGTK
YRKEPSACPI CGKVFSCRSN MNKHLLTHGD KKYTCEICGR KFFRVDVLRD HIHVHFKDIA
LMDEQEREEF IRKIGISVDS SDDTDDEDED DEPETHKYSC KKCPVTFLKG RDYLKHIMDL
HKERGYGCII CNRRFALKAT YNAHLVIHRE QLPDPAVQRY IHPCEMCGRI FNSIGNLERH
KVIHTGVKSH GCDKCGKSFA RKDMLKEHLR VHDNIRDFLC AECGKGMKTK HALRHHMKLH
KGIKEYECKE CNRKFAQKVN MLKHYKRHTG IKDFMCELCG KTFSERNTME THKLIHTVGK
TWSCVVCDKK YVTEYMLQKH VQLTHEKVEA QTCHLCGTKV STRASMNRHM RRKHPEVVTE
RIDDFDELQE VSTIDESSIS IAQPDLTLEK EAAEKPPRTP RASRKKPKQP EEPELSDSDE
YADFSGKDAE YSAAIGGDET SSAVQSIQQV VVLADPNTSS ASSPNGSAGL KNITVTPITS
QAPTQFTSLQ PVAVGHLTAS DHRPLNLDSP ILTVTFDTVS GSAMLHNRPA ELTAETVGPG
GATTGPQSVA HFINLTTFVN PMGLPLEAPT LAWRPVTQAE GIQSAPVVDG PPGDAQDAQT
PEQARQAQAA QQQANTTQQM FSY
//
