ID A0A3P8Z9J6_ESOLU Unreviewed; 823 AA.
AC A0A3P8Z9J6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Terminal nucleotidyltransferase 4A {ECO:0000313|Ensembl:ENSELUP00000025451.2};
GN Name=TENT4A {ECO:0000313|Ensembl:ENSELUP00000025451.2};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000025451.2, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000025451.2, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000025451.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8Z9J6; -.
DR STRING; 8010.ENSELUP00000025451; -.
DR Ensembl; ENSELUT00000037171.2; ENSELUP00000025451.2; ENSELUG00000024141.2.
DR GeneTree; ENSGT00940000157811; -.
DR InParanoid; A0A3P8Z9J6; -.
DR OMA; KWGSRVH; -.
DR Proteomes; UP000265140; LG10.
DR Bgee; ENSELUG00000024141; Expressed in ovary and 14 other cell types or tissues.
DR GO; GO:1990817; F:poly(A) RNA polymerase activity; IEA:InterPro.
DR GO; GO:0016070; P:RNA metabolic process; IEA:UniProt.
DR CDD; cd05402; NT_PAP_TUTase; 1.
DR Gene3D; 1.10.1410.10; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002058; PAP_assoc.
DR InterPro; IPR002934; Polymerase_NTP_transf_dom.
DR InterPro; IPR045862; Trf4-like.
DR PANTHER; PTHR23092; POLY(A) RNA POLYMERASE; 1.
DR PANTHER; PTHR23092:SF24; TERMINAL NUCLEOTIDYLTRANSFERASE 4A; 1.
DR Pfam; PF01909; NTP_transf_2; 1.
DR Pfam; PF03828; PAP_assoc; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81631; PAP/OAS1 substrate-binding domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265140}.
FT DOMAIN 302..402
FT /note="Polymerase nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF01909"
FT DOMAIN 464..523
FT /note="PAP-associated"
FT /evidence="ECO:0000259|Pfam:PF03828"
FT REGION 29..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 64..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 116..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 213..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 597..674
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 739..781
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 794..823
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 218..232
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 617..659
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 739..757
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 823 AA; 91086 MW; A0F317E07E797A14 CRC64;
MDPRVAWIQP EQKGPANALW MRVWETSQVQ GNPGQQHHHH HHHNNQNHNL CVNSPAKDVL
KNVATSASSK NIGSSSTVGL RSSSHHGISN GTTSNHGTAF SSFGVTLANG NVHNVNSLTP
SNGNGLTTGL GEEEMPQKTL VSSSVESRTD SPSSNCFLGR TNGGNVTGNM NKNAGVNLFF
NFSESMHNNV NHYHHQRHHQ EPQYNFQQNC VKRHPTHPPA TLNHHTHHPG RRKSDNKAST
YGMNYLLSNW NNGNYVNSAT GTPWKTRKYS AGVDGLHEEV VDFYNFMSPR PEEAAMRKEV
VDRIETVIKE LWPTARVQIF GSFSTGLYLP TSDIDLVVFG KWERPPLQQL EQALRNHNVA
EPSTIKVLDK ASVPIIKLTD LETDVKVDIS FNVETGVKAA HFIKDYTKKY PVLPYLIFVL
KQFLLQRDLN EVFTGGISSY SLILMVISFL QLHPRIDASN PSINLGILLI EFFELYGRHF
NYLKTGIRIK NGGAYMAKED MMKVMTNGYR PSMLCIEDPL MPGNDVGRSS YGAMQVKQVF
DYAYIVLGHA VTPLARSYPN NHLDSILGRI IKVTQEVIDY RDWIMKKWGC RHIARMESRG
SPPEQEPARC VLGSTGDDQR DSVSPHSPAD SPMSLSSPHQ HSSASSVSSL SGSDNDSDST
PCPGPPPTLP PFHLQAVGVT LHPGLALGKH QGISQHHLML SPGSQACMSL PSGLTIHSLP
GRQVGIDGHP LPPFFHMPPP THHNPHAHVP SSPQPLSSPH PASDMHQNGP KYPMKGSHSP
AVVHSPVLVN RSHTHPLAHT HSNPQYRTHR RWRKRDSLPA SLS
//
