ID A0A3P8ZIX0_ESOLU Unreviewed; 671 AA.
AC A0A3P8ZIX0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Anosmin-1 {ECO:0000313|Ensembl:ENSELUP00000028681.2};
GN Name=ANOS1 {ECO:0000313|Ensembl:ENSELUP00000028681.2};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000028681.2, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000028681.2, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000028681.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3P8ZIX0; -.
DR STRING; 8010.ENSELUP00000028681; -.
DR Ensembl; ENSELUT00000012780.2; ENSELUP00000028681.2; ENSELUG00000005359.2.
DR GeneTree; ENSGT00440000033720; -.
DR Proteomes; UP000265140; LG16.
DR Bgee; ENSELUG00000005359; Expressed in brain and 9 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0030414; F:peptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00063; FN3; 3.
DR CDD; cd00199; WAP; 1.
DR Gene3D; 4.10.75.10; Elafin-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR042447; Anosmin-1.
DR InterPro; IPR040957; Anosmin-1_Cys_box.
DR InterPro; IPR036645; Elafin-like_sf.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR008197; WAP_dom.
DR PANTHER; PTHR14131; ANOSMIN; 1.
DR PANTHER; PTHR14131:SF6; KAL1.1-RELATED; 1.
DR Pfam; PF17869; Cys_box; 1.
DR Pfam; PF00041; fn3; 2.
DR Pfam; PF00095; WAP; 1.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00217; WAP; 1.
DR SUPFAM; SSF57256; Elafin-like; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS51390; WAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..671
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5027699430"
FT DOMAIN 123..172
FT /note="WAP"
FT /evidence="ECO:0000259|PROSITE:PS51390"
FT DOMAIN 178..282
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 288..397
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 542..647
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
SQ SEQUENCE 671 AA; 75500 MW; E4FD7EB73EC25C8F CRC64;
MLPRSVTVCV TMCLWIIVLS THGTIAARSK QDDSFFTGSI YRARCASRCL SLHITRISAF
FKHSQNNGSL VWCQNHKQCS KCLEPCKEFW DLKENQCQDL CEPLFPKKHY ECLTSCEFLK
SVEGVKQGDC PAPDKASGFA AACVESCEED GECSTVKKCC SNDCGHTCQT PKNLYKGAPL
KPRKELVFLE QPSGGLEIRW SSKFNISVEP VLYVVQRRWN YGIHPSEDDA TEWESAAQTT
EERVQLADIR ASRWYQFRVA AVNVHGTRGF TAPSKHFRSS RDPAAPPSPD SLRVTNMTVG
AEGTMTARLN WTLPEEPDIP VHHYKVFWSW TVPGKSLVPS KKKRRMITNG AQSWVDMEGL
LTNSSYTVEL QAVTYWGQVR LKSSKASLQF NTTTQNVSVS KKDKKEEVMI PVGSSLGKRP
AGTLEVGTPF YQDGQLQVRV YWKNRGDPLV SRYHVQWMPE YCSHNDTREP EKSVTQENYI
NLPGLLFSCK YKVTVHVLKS KRRAKDESAT FLTPSCSTIR SKSHKHIPCP GEGAPAPKVL
AKPENLTASF SIHEGNITGN FLWRVSRVLA HQRITGFQVT WAEVTTESRQ NSLPNSIISQ
SQILPPDHNL LVVSNLRPAT YYRLEVQVIT SGGEGPATVK TFQTPSVLPV LQHRPRLRQH
HAHQKPSAER H
//
