ID A0A3P8ZJ20_ESOLU Unreviewed; 285 AA.
AC A0A3P8ZJ20;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Voltage-dependent calcium channel gamma-5 subunit {ECO:0000313|Ensembl:ENSELUP00000028834.1};
GN Name=CACNG5 {ECO:0000313|Ensembl:ENSELUP00000028834.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000028834.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000028834.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000028834.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
CC {ECO:0000256|ARBA:ARBA00007111}.
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DR RefSeq; XP_012991283.1; XM_013135829.2.
DR RefSeq; XP_019906248.1; XM_020050689.1.
DR RefSeq; XP_019906249.1; XM_020050690.1.
DR AlphaFoldDB; A0A3P8ZJ20; -.
DR STRING; 8010.ENSELUP00000028834; -.
DR Ensembl; ENSELUT00000012390.2; ENSELUP00000028834.1; ENSELUG00000005574.2.
DR GeneID; 105026134; -.
DR KEGG; els:105026134; -.
DR GeneTree; ENSGT01050000244961; -.
DR InParanoid; A0A3P8ZJ20; -.
DR OMA; EYMMPTS; -.
DR OrthoDB; 2957055at2759; -.
DR Proteomes; UP000265140; LG11.
DR Bgee; ENSELUG00000005574; Expressed in brain and 1 other cell type or tissue.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006816; P:calcium ion transport; IEA:InterPro.
DR Gene3D; 1.20.140.150; -; 1.
DR InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR InterPro; IPR008369; VDCC_g5su.
DR InterPro; IPR008368; VDCC_gsu.
DR PANTHER; PTHR12107; VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT; 1.
DR PANTHER; PTHR12107:SF4; VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-5 SUBUNIT; 1.
DR Pfam; PF00822; PMP22_Claudin; 1.
DR PRINTS; PR01792; VDCCGAMMA.
DR PRINTS; PR01793; VDCCGAMMA5.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 285 AA; 31607 MW; 4AB9C183486808E2 CRC64;
MLVSSDLTSM SVCGRKALTL MSSIFAMSGL GLLGVAVSTD YWLYMEEGVI LPQNQSTDIR
TSLHSGLWRV CFLAGEEAGS CFTIEYVMPM NVQLSSESTV SVLKMIRSAT PFPMVSLFFM
FIGFVLNNIG HVRPQRTILA FVSGIFFILS GLALVVGLVL YISSINDEML NRTKSSGSHF
SYRYGWSFAF AAISFLLTES AGVMSVYLFM KRYTAEEMYQ PHRPGFYRPR LSNGSDHSSQ
FLHPEAWARG RSPSDISSEA SFQMSASYPT LLQCPDYDQV SSSPC
//
