ID A0A3P8ZJV8_ESOLU Unreviewed; 286 AA.
AC A0A3P8ZJV8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=C1q and TNF related 7 {ECO:0000313|Ensembl:ENSELUP00000029021.1};
GN Name=C1QTNF7 {ECO:0000313|Ensembl:ENSELUP00000029021.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000029021.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000029021.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000029021.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR RefSeq; XP_010870443.1; XM_010872141.2.
DR RefSeq; XP_010870444.1; XM_010872142.2.
DR RefSeq; XP_019904406.1; XM_020048847.1.
DR RefSeq; XP_019904407.1; XM_020048848.1.
DR RefSeq; XP_019904408.1; XM_020048849.1.
DR AlphaFoldDB; A0A3P8ZJV8; -.
DR Ensembl; ENSELUT00000011992.2; ENSELUP00000029021.1; ENSELUG00000005765.2.
DR GeneID; 105011807; -.
DR GeneTree; ENSGT00940000159588; -.
DR OrthoDB; 3013859at2759; -.
DR Proteomes; UP000265140; LG08.
DR Bgee; ENSELUG00000005765; Expressed in stomach and 10 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR001073; C1q_dom.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR15427:SF24; COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 7; 1.
DR PANTHER; PTHR15427; EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER; 1.
DR Pfam; PF00386; C1q; 1.
DR Pfam; PF01391; Collagen; 1.
DR PRINTS; PR00007; COMPLEMNTC1Q.
DR SMART; SM00110; C1Q; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS50871; C1Q; 1.
PE 4: Predicted;
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..286
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5030079186"
FT DOMAIN 141..277
FT /note="C1q"
FT /evidence="ECO:0000259|PROSITE:PS50871"
FT REGION 36..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..78
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 286 AA; 29982 MW; 4F1DA188E4C8096F CRC64;
MWLFVGVAFL CHCVIGQLLD AKVRGAPPRL ICSVPGLPGT PGKPGPNGPP GADGNMGIPG
RDGRDGRKGE KGEKGEAGGK GKVGPTGKLG QRGDRGPGGK RGPNGERGDG GQPGPLGPIG
EKGDKGQQGP RGTAGVCRCG SLVPKAAFSV GITSSYPAEK EPIKFNKVLF NEGGHYNPAT
GKFICAYPGI YYFSYDITLA NKHLAIGLVQ NGQYRIKTFD ANTGNHDVAS GSTVMFLNPE
DEVWLEIFFP GQNGLFTDAS WSDSLFSGFL LYADTNYLDS LAEDYA
//
