ID A0A3P8ZK72_ESOLU Unreviewed; 1733 AA.
AC A0A3P8ZK72;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=LIM and calponin homology domains-containing protein 1-like {ECO:0008006|Google:ProtNLM};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000028848.2, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000028848.2, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000028848.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR Ensembl; ENSELUT00000012360.2; ENSELUP00000028848.2; ENSELUG00000005593.2.
DR GeneTree; ENSGT00950000183159; -.
DR Proteomes; UP000265140; LG25.
DR Bgee; ENSELUG00000005593; Expressed in muscle tissue and 7 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08368; LIM; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR031865; DUF4757.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR15551:SF3; LIM AND CALPONIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR15551; LIM DOMAIN ONLY 7; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF15949; DUF4757; 2.
DR Pfam; PF00412; LIM; 1.
DR SMART; SM00033; CH; 1.
DR SMART; SM00132; LIM; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 22..137
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 1666..1732
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 282..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 394..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 482..541
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 561..600
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 649..683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 713..803
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 997..1100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1129..1403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1586..1655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1447..1484
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 10..25
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..213
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..232
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..426
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 501..529
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 662..676
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 764..778
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 784..803
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 997..1030
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1031..1045
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1046..1083
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1084..1099
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1130..1184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1210..1334
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1350..1403
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1604..1655
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1733 AA; 194430 MW; 390CF94D5F4CC23E CRC64;
MASAAAEQEE PLRPPDEPSH SEPAFREAQK WIEEVTGKSF GEKDFRSGLE NGILLCELLC
SIRPGLVKKI NRLPTPIAGL DNLSVFLRGC KEMGLTGSQL FDPGDLQATS ADSRDSGCSR
KLKNVLVTVF WLGKAVSVCP SYNGPVLNLK EFEELLSHMR TEDKLGSGVR DSGYDCWDSE
SLSPPQHTRD DSLDSLDSYG SQSQTSPSLE GITHGDSESE AANRKPDVHR DDMLARRTAV
GESRSSVPFN QFLPNRSNAT AYVPTSRRRP RPEDVEQCSV PLPIQEERKG SKEGGGTFKK
PLGPRSRNPK TVTWAPEGGG LKEEEEGLRQ EEVLKQEEEE QQRLKRLQKA GIKVLPAVIR
YGRPTPPFEQ QEVRSPSPDI ILRCHNDFLT NQKATWDSDS EGEAESGGVR TVPDIRRDDL
ASRRNPRPHA APRTHQYIPA PACSQRDRQV WENIRQASHR ALMERMEVER RTSEAECDII
IRRNNPFLNP SSQQDEEEEE EGTGRGVKVR LPNKTKDDLA RRKAQSRQLP SHRDGPMSFV
PASITRSDLD RWERLKMAEP SHMGGVNVSQ NQPLKYDPPT VTPPLLESER GEREEEEDDG
KVLDLQRDNM NPILPLPGSK RPVQEVVTDR KRQQPWCFAE TPQQHTDMAT VVRSPVPRND
SYDDDGDDEE ESTVPDLEKD DMLARRTREY QRSMGGHSHS FNLFLPVPGA AQHLRGGAKP
LSKQRQQPDS SCVSPAAGPV AMPSKTTTRK CLLVREDNLS LSPTPPPSSN PPTTPPPLDQ
ISEGRGDEGG KEREKEKEME GGIEEGIEGG IERELGNKEE SRKVGGESHR RPFWLEDDDL
PTMMLSRRVC STSEESESMS MIDMPYELEG AGLMEHLGQS RYKRMQDQYT YCQEEEEEWR
NDLARWKSRR RGVSQDLIRK EEERKMMERR MKEEEGHAQK KNIKTYREIV EEKERREAEL
CAAYKRAGSK EEAAMVLQRY ALRFTISDAT LESLQLPRTT STQNHIKQNP VSKTTGTDQN
LVPGGTRTDG ESSKTKTDQE SRPTDTQQDH NQYTKATPLT QQNHTEPVTQ HKPQNHTEPQ
TQHTVPPPIS PPPRPLPLLT AKPYSRLSLQ PVKIPQTGHQ LFKDPQIRHQ PVKNPQTGQQ
PLRDPQTRHQ PVKNPQTGHQ PVKDPQTGHQ PIMDSQTGHQ FHKDPQTGHQ PVMDPHTGHQ
PVKDPQTGHQ PVKDPQTGHQ PVKDPQTGHQ PVKDPQTGLQ PVKDPQTGHQ PVKDPQTGHQ
PVKDPQTGHQ PVKDPQTGHQ PVKDPQTGHQ PVKDPQTGHQ PVKDPQTGHQ PVKDPQTGHQ
PVKDPQTGHQ PVKDPQTRHQ PVKDPQTGHQ PVKDPQTGHQ PVKVNSSVGL SRRSGEELGS
DSTWLSNQNT YSSSVTEGHQ GSSVTIESPM LNLAKRVNHW VWNPEEERSR QEKWQQEQER
LLQEEYLREQ EKLKVEWERA QTEVEEEERR HNEEERKILE ETATHLFQAP PIQISIQIEP
IAPAPQIYKT EPIAPAPQIY KTEPIAPAPQ IYKTEPIAPA PQIYKTEPIA PAPQIYKTEP
IAPALQIYKT EPIAPAPQIY KSEASAYENS QDQHAMTPVP FTPDASWESE SSMGQMTSLD
RTSQQDLPSS EKRSGSYDCP HSPLSSSISS SSPQPFLPSR CVSGKRLCSG CGQLLEKGAA
MSIDTLGLYY HLACFKCGVC KGQLGDSSSG TDVRIRNGLL SCRDCYLASH AVG
//
