ID A0A3P8ZM84_ESOLU Unreviewed; 574 AA.
AC A0A3P8ZM84;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Transcription factor COE3 {ECO:0000313|Ensembl:ENSELUP00000029826.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000029826.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000029826.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000029826.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU004489}.
CC -!- SIMILARITY: Belongs to the COE family. {ECO:0000256|ARBA:ARBA00010340,
CC ECO:0000256|RuleBase:RU004489}.
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DR RefSeq; XP_010868264.1; XM_010869962.3.
DR AlphaFoldDB; A0A3P8ZM84; -.
DR STRING; 8010.ENSELUP00000029826; -.
DR Ensembl; ENSELUT00000009925.2; ENSELUP00000029826.1; ENSELUG00000001507.2.
DR GeneID; 105010579; -.
DR GeneTree; ENSGT00950000182859; -.
DR OrthoDB; 3641706at2759; -.
DR Proteomes; UP000265140; LG06.
DR Bgee; ENSELUG00000001507; Expressed in embryo and 10 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd11606; COE_DBD; 1.
DR CDD; cd01175; IPT_COE; 1.
DR Gene3D; 1.10.287.4280; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.40.3180; Transcription factor COE1, DNA-binding domain; 1.
DR InterPro; IPR032200; COE_DBD.
DR InterPro; IPR038173; COE_DBD_sf.
DR InterPro; IPR032201; COE_HLH.
DR InterPro; IPR038006; COE_IPT.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR003523; Transcription_factor_COE.
DR InterPro; IPR018350; Transcription_factor_COE_CS.
DR PANTHER; PTHR10747; TRANSCRIPTION FACTOR COE FAMILY MEMBER; 1.
DR PANTHER; PTHR10747:SF4; TRANSCRIPTION FACTOR COE3; 1.
DR Pfam; PF16422; COE1_DBD; 1.
DR Pfam; PF16423; COE1_HLH; 1.
DR Pfam; PF01833; TIG; 1.
DR SMART; SM00429; IPT; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR PROSITE; PS01345; COE; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|RuleBase:RU004489};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004489};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU004489};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004489};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004489};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU004489};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004489};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004489}.
FT DOMAIN 253..337
FT /note="IPT/TIG"
FT /evidence="ECO:0000259|SMART:SM00429"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 437..477
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 518..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 574 AA; 62914 MW; 30881441A8D67790 CRC64;
MFGIQETISR GGTTMKEEPL GGLNSVRSWM HTAGVVDANT AAQSGVGLAR AHYEKQPPSN
LRKSNFFHFV LALYDRQGQP VEIERTAYVD FVEKEKEPNS EKTNNGIHYK LQLLYSNGVR
TEQDLFIRLI DSMTKQAIIY EGQDKNPEMC RVLLTHEIMC SRCCDKKSCG NRNETPSDPV
IIDRFFLKFF LKCNQNCLKN AGNPRDMRRF QVVVSTTVNV DGHVLAVSDN MFVHNNSKHG
RRARRLDPSE AATPCIKAIS PSEGWTTGGA TVIIIGDNFF DGLQVVFGTM LVWSELITPH
AIRVQTPPRH IPGVVEVTLS YKSKQFCKGA PGRFVYTALN EPTIDYGFQR LQKVIPRHPG
DPERLPKEVL LKRAADLVEA LYGMPHNNQE IILKRAADIA EALYNVPRNH NQIPSLANTA
SHGMMGVNSF SGQLAVNVSD SQGNDQGYSR NTSSVSPRGY ITSSTPQQTS YNTVSNSMNG
YGNSGMSNLG VPGSPGFLNG SSANSPYGIK QKSAFAPVVR PQASPPPSCT SANGNGLQGE
PPSPPHPFPS DYWADTAAHA SVRFAMSGLV VPPM
//
