ID   A0A3P8ZRM6_ESOLU        Unreviewed;       796 AA.
AC   A0A3P8ZRM6;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=SID1 transmembrane family member 2 {ECO:0000313|Ensembl:ENSELUP00000031535.1};
GN   Name=SIDT2 {ECO:0000313|Ensembl:ENSELUP00000031535.1};
OS   Esox lucius (Northern pike).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC   Esocidae; Esox.
OX   NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000031535.1, ECO:0000313|Proteomes:UP000265140};
RN   [1] {ECO:0000313|Ensembl:ENSELUP00000031535.1, ECO:0000313|Proteomes:UP000265140}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=25069045;
RA   Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA   von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT   "The genome and linkage map of the northern pike (Esox lucius): conserved
RT   synteny revealed between the salmonid sister group and the Neoteleostei.";
RL   PLoS ONE 9:e102089-e102089(2014).
RN   [2] {ECO:0000313|Ensembl:ENSELUP00000031535.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the SID1 family.
CC       {ECO:0000256|ARBA:ARBA00006618}.
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DR   AlphaFoldDB; A0A3P8ZRM6; -.
DR   Ensembl; ENSELUT00000005519.2; ENSELUP00000031535.1; ENSELUG00000009317.2.
DR   GeneTree; ENSGT00390000010091; -.
DR   Proteomes; UP000265140; LG01.
DR   Bgee; ENSELUG00000009317; Expressed in digestive tract and 15 other cell types or tissues.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR025958; SID1_TM_fam.
DR   PANTHER; PTHR12185:SF16; SID1 TRANSMEMBRANE FAMILY MEMBER 2; 1.
DR   PANTHER; PTHR12185; SID1 TRANSMEMBRANE FAMILY MEMEBER; 1.
DR   Pfam; PF13965; SID-1_RNA_chan; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        256..281
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        413..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        471..490
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        511..534
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        571..590
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        596..618
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        678..699
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        711..731
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        762..781
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   796 AA;  90158 MW;  7E58CC6C4951C121 CRC64;
     MFLRSCWKSR HKPDSGSVLV WLQLRYVALL WLCVTHLGCA GAEKTVVQKD AEFDITYNDT
     ARSDNQTIYA FNHTVSRNRT EGVRVTVDVL SEGTESSPIL FVVRQKQAVL SFQVPLILRG
     LTDKKFSFTA SPSQPQYFKY VFPDGVDTVI VKVNSEMTFP CSVMSIQDIQ CPVYDLDNNV
     AFIGMYQTMT KKGAITVQRK DFPSNSFYVV VVVKTEDEAC GGPLRFYPLR PDELIDAGNR
     SKTLDVVVSP AIKSEVYVMG MLFCLGIFLS FYLLTFLVAC VENKRMHRRR EGLLHPVDMS
     PAETAPLLGK PAVTPVSPYD QYGSFADNAS TLSSEAITDS IASDANYGYM ERSLESVTGR
     SRHESLSSVE EDDYDTLADI DSDKNIVRTK KYLCVSDLAR KDKRVLSKKY QIYFWNIATI
     GVFYALPVIQ LVITYQTVVN VTGNQDICYY NFLCAHPLGN LSAFNNILSN LGYVMLGLLF
     LLIVLQRDII HSKALERNEL NALECGIPKH FGLFYAMGTA LMMEGLLSAC YHVCPNYTNF
     QFDTSFMYMI AGLCVLKLYQ KRHPDINASA YTAYACLAAV IFFSVLGVVF GKGNMVFWIV
     FSVIHILATL LLSTQLYYMG RWRLDSGILR RMVYVIYTDC IRQCSGPMYI DRMVLLVMGN
     IVNWSLAAYG LLERPNDFAS YLLAIAICNL LLYFAFYIIM KLRSGERIGC MSLVCILFTA
     VVWGFALFFF FQGLSTWQKT PAESREHNRD CIVLSFFDDH DIWHFLSSIA MFGSFLVLLT
     MDDDLDDVQR DKIFVF
//