ID A0A3P8ZTS7_ESOLU Unreviewed; 275 AA.
AC A0A3P8ZTS7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Tetraspanin-8 {ECO:0000313|Ensembl:ENSELUP00000032300.2};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000032300.2, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000032300.2, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000032300.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_010893445.1; XM_010895143.3.
DR AlphaFoldDB; A0A3P8ZTS7; -.
DR Ensembl; ENSELUT00000003566.2; ENSELUP00000032300.2; ENSELUG00000010209.2.
DR GeneID; 105024880; -.
DR GeneTree; ENSGT00990000205092; -.
DR OrthoDB; 4269119at2759; -.
DR Proteomes; UP000265140; LG18.
DR Bgee; ENSELUG00000010209; Expressed in bone element and 14 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.1450.10; Tetraspanin; 1.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR008952; Tetraspanin_EC2_sf.
DR PANTHER; PTHR19282; TETRASPANIN; 1.
DR PANTHER; PTHR19282:SF158; TETRASPANIN TSPE-RELATED; 1.
DR Pfam; PF00335; Tetraspanin; 1.
DR SUPFAM; SSF48652; Tetraspanin; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 221..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 275 AA; 30464 MW; BF2F184D7856DD41 CRC64;
MGQINIWIKG AFITVCLLIG IISSLLLAIT LFGHGYAHQT EEIEELLPTI SVVYVIGGGT
LALTIIGAYG ACKKKKWAVF LFSLGMTVGS LYLLAESISA YQMKEEIKEE IREHYKILMP
LTNPSEKDLG RIHKIQNNFK CCGVENGYKD WGDEIPISCL CSEDNRAFKC VDSGNNTRFI
VHHSSNNMSE EDHGLTKEHR LVYAEPCIPV LINSFNFVID LILGICFAVT LLWAVGASLS
ITILCQMRRT LNVPPVVFTS KVSQYTQLSD PAANA
//
