ID A0A3P8ZUU6_ESOLU Unreviewed; 427 AA.
AC A0A3P8ZUU6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=E3 ubiquitin-protein ligase TRIM21 {ECO:0000313|Ensembl:ENSELUP00000032259.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000032259.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000032259.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000032259.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_010897475.1; XM_010899173.3.
DR RefSeq; XP_010897476.1; XM_010899174.2.
DR AlphaFoldDB; A0A3P8ZUU6; -.
DR Ensembl; ENSELUT00000003690.2; ENSELUP00000032259.1; ENSELUG00000010097.2.
DR GeneID; 105027203; -.
DR KEGG; els:105027203; -.
DR GeneTree; ENSGT00940000163587; -.
DR InParanoid; A0A3P8ZUU6; -.
DR OMA; WEVEVSP; -.
DR OrthoDB; 4206148at2759; -.
DR Proteomes; UP000265140; LG24.
DR Bgee; ENSELUG00000010097; Expressed in liver and 5 other cell types or tissues.
DR CDD; cd13733; SPRY_PRY_C-I_1; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR24103:SF698; B30.2_SPRY DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265140}.
FT DOMAIN 239..427
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 22..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..61
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 427 AA; 48686 MW; 6A5ABE78678AE4E5 CRC64;
MMVDTGVKHF NTLRKKQDKR LETVEVTHSE PWNKPTLSNN NEGQSETWAH SGPWTKPLSS
SKHGLEQMQT YQECLKLIRQ LAEDVKNISQ LARRRGVMDG GGPIAPLSLE SSKSLIFVWA
EELNQLAPLQ KTSASATHVQ SMRVRRDLDG GKDRERKNRS LERENQLVIE WAKELKSVSE
ISGLSDKDIN RLLCPGAIKE PRLASVLPLL EFFAWSLLSQ DNEEDVLKLW LSTKQRALRK
PKYIPISVWN WICSASDSVS LDPFSSHPWL AISDDNRQVW EGPQRTDTVN HPQRFDRWSC
VLGSPTISTG RHYWEVELSA EGGWRLGVTD VNAPRKGLFS MTPANGFWTL WKGTQNIIWA
CGEPQTKITV RALLRIVGVY LDFEEGQVSF YDVENRVHIY TFSDKFKGRV VPVFGCHDGD
TKISIRY
//
