ID A0A3P8ZWL0_ESOLU Unreviewed; 706 AA.
AC A0A3P8ZWL0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Actin binding LIM protein 1a {ECO:0000313|Ensembl:ENSELUP00000033275.2};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000033275.2, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000033275.2, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000033275.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8ZWL0; -.
DR STRING; 8010.ENSELUP00000033275; -.
DR Ensembl; ENSELUT00000001088.2; ENSELUP00000033275.2; ENSELUG00000011523.2.
DR GeneTree; ENSGT00950000182850; -.
DR InParanoid; A0A3P8ZWL0; -.
DR Proteomes; UP000265140; LG06.
DR Bgee; ENSELUG00000011523; Expressed in spleen and 8 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd09327; LIM1_abLIM; 1.
DR CDD; cd09328; LIM2_abLIM; 1.
DR CDD; cd09329; LIM3_abLIM; 1.
DR CDD; cd09330; LIM4_abLIM; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 4.
DR InterPro; IPR032402; AbLIM_anchor.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24213; ACTIN-BINDING LIM PROTEIN; 1.
DR PANTHER; PTHR24213:SF18; ACTIN-BINDING LIM PROTEIN 1; 1.
DR Pfam; PF16182; AbLIM_anchor; 2.
DR Pfam; PF00412; LIM; 4.
DR SMART; SM00132; LIM; 4.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 6.
DR PROSITE; PS00478; LIM_DOMAIN_1; 2.
DR PROSITE; PS50023; LIM_DOMAIN_2; 3.
PE 4: Predicted;
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT TRANSMEM 659..679
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 49..108
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 109..168
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 177..236
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 289..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 372..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 466..570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 586..643
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..307
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..395
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 541..570
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 600..623
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 706 AA; 79206 MW; 313805327F6BBF63 CRC64;
MGERSTVEQQ KQPPSDGGLC NYAQKIGSCF GLDVAHAQDT HHSSEKPLIQ CYKCGQPCKG
EVLRVQSKHF HLKCFTCKVC GCDLAQGGFF MKNGDYLCTL DYQRMHGTRC NGCGDFVEGE
VVTALGKTYH PACFVCTICK RPFPAGDRVT FNGKDCLCQY CVQPTSPGPG KDIIDSNCCT
GCGRDIKNGQ ALLALEKQWH LGCFKCKACQ KVLTGEYISK DGAPYCEKDY QIHFGVQCEA
CQQFITGKVL EAGDKHYHPT CARCSRCNQM FTEGEEMYLQ GSTVWHPGCK DTTRTEERQR
ERPSRSSSDS ICSRPGSSIP GSPGHTIYAK VDNEILDYRD LAAIPKVKAI YDIERPDLIT
YEPLYTMSLD EKDERRESVG ELHTARRERS PMTDDRSSRN MSPTPSAEGC YDMRERILQR
STSQGSIGSP VYNRHSYTPL SRSPQHFHRP EAMTGMQKLC SALCSNSVGS SSINDSRPTS
PFRHHFLPHS QGTEPANGRS SPIPQRPDSR PVTPPLSLTP KHFHLPDQGI NIYRKPPIYK
QHGSEGGRRR SREEEEEEAL KRKQLHEEHI NKIQSGLGKL IMKEENEKDQ IRERHARSQS
AQRYQPQPTK CDGDDSKTSS LPGYGRNGLH RPQSTDFTQY NSHGDMGGGG REFQVCPSFA
YPQMLFIMFF ILHVFCSLIS QGRKPHAILT VNPLQLNACI KVNTMQ
//
