ID A0A3P8ZXW6_ESOLU Unreviewed; 402 AA.
AC A0A3P8ZXW6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Zgc:158846 {ECO:0000313|Ensembl:ENSELUP00000033582.2};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000033582.2, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000033582.2, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000033582.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3P8ZXW6; -.
DR STRING; 8010.ENSELUP00000033582; -.
DR Ensembl; ENSELUT00000000312.2; ENSELUP00000033582.2; ENSELUG00000032891.1.
DR GeneTree; ENSGT00940000161090; -.
DR InParanoid; A0A3P8ZXW6; -.
DR OMA; SEERFAC; -.
DR Proteomes; UP000265140; LG17.
DR Bgee; ENSELUG00000032891; Expressed in bone element and 15 other cell types or tissues.
DR GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR003054; Keratin_II.
DR PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45616:SF21; KERATIN, TYPE II CYTOSKELETAL 7; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01276; TYPE2KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 1.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140}.
FT DOMAIN 1..242
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 312..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 135..162
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 186..213
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 402 AA; 44399 MW; 70A1C8E1277326A5 CRC64;
MRLEADLHNM KGIVEDFKTK YEDEIHKRNE SENNFVILKK DADAAYMIKM ELEAKLDGLN
DEIQFLRSLF DLELRELQGQ IKDTSVVVEM DNSRNLDMDS IVAEVRAQYE DIANRSRAEA
ESWYTQKYEQ MQVSANKYGD DVKNTKAEIA DINRKILRYQ SEIDMIKGQV RANQIAEAED
RGELAVKDAK LRIKDLENAL QRAKQDMTMQ VRQYQELMNV KLALDIEIAT YRKLLEGEES
RYSSLSSFPP LNYHSYPMES NRPSSYVSSS VGGYKGVHDN SRVSRGFDLP GGTSGIQVCT
SSDADASVTL GAGNGTSRDT DASVTLGAGN GTSRDTDVSV TLGAGNGTSR EVDVSVTVNS
SSVTVCKTQT TVVTSLEGEV ISEVASQAVA EQAEEQAATT GE
//
