ID A0A3P8ZY16_ESOLU Unreviewed; 1783 AA.
AC A0A3P8ZY16;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=NHS actin remodeling regulator {ECO:0000313|Ensembl:ENSELUP00000033476.1};
GN Name=NHS {ECO:0000313|Ensembl:ENSELUP00000033476.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000033476.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000033476.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000033476.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_010884773.1; XM_010886471.2.
DR Ensembl; ENSELUT00000000584.2; ENSELUP00000033476.1; ENSELUG00000011746.2.
DR GeneID; 105019920; -.
DR GeneTree; ENSGT00950000182963; -.
DR OrthoDB; 5355272at2759; -.
DR Proteomes; UP000265140; LG22.
DR Bgee; ENSELUG00000011746; Expressed in camera-type eye and 9 other cell types or tissues.
DR Gene3D; 1.20.5.340; -; 1.
DR InterPro; IPR024845; NHS-like.
DR PANTHER; PTHR23039; NANCE-HORAN SYNDROME PROTEIN; 1.
DR PANTHER; PTHR23039:SF10; NANCE-HORAN SYNDROME PROTEIN ISOFORM X1; 1.
DR Pfam; PF15273; NHS; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140}.
FT REGION 141..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 405..514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 521..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 575..621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 642..709
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 803..864
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 899..928
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 975..1123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1221..1331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1360..1592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1612..1644
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1666..1783
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 42..76
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 141..155
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..206
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 416..447
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..486
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 586..603
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 650..670
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..709
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 840..862
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 910..928
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 975..1002
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1028..1050
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1068..1100
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1221..1235
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1291..1314
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1402..1436
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1437..1454
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1520..1539
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1561..1583
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1616..1644
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1683..1703
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1714..1771
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1783 AA; 193169 MW; 1DEF76D6E1D0EA38 CRC64;
MPFAKRIVEP QLLCRQPIPN DEGSLNIEDL CSINNVVLSR TLRQLSDLAK HACSLFQELE
NEIMSTNQRV WVLQNKIGKI QQTANGLDPK KEAVPVSNLD VESKLTAHYR APWHQQHNVF
HPCSRPPCVE ELHRHAQQSL RALHRDHRQR SNSRERRVAI SISAAPPMPS FPSPRTLRRQ
EQRGRHSRSE RQMRETEIQT VQRKERPVRD VDFQTIQRKC DRARSPSPSD CCFLTPWSRK
AATTTDSGEE AMVGHRSKCA IPNPPSTLDK QTNWSKALPL PTPQERMKSD PAVVSSCIIP
INVTGVGFDR EASVRCSLVH SQSVLQRRRK LRRRKTITGI PRRVQQDMDS DESPVARERT
VIVHANTHLS LCQEEGSLRG GHTKDSGCQT DDCLIAAGGA PSRRRIRAQR GGQGGVPASL
SHSTGNISSL PDHPDTAMYT ASGSRLRSRS LPREGGRIRD EDQDDSDEDE DDEEDEDDEE
ELSPYETEDF LPGAGPRMLK DEEESTDDQA GPDLQLGSLK RMQHSQGGSP EHIWMERGRS
RLPRKADMGS CEISSSSDTF SSPIHCISTT GVLGGQLDHK EDHQSSSGNW SGSSSTCPSQ
TSETLPPAPS PPLTGSSHCD SELSLNAAPH AIDDLTGFII DPYHSDRPQG QGHRSCSFTS
SATDQLDDAG VSTASEGEWA YPQDQADNDQ EQPCGQDFSP RRSSRGDQTR LNFTSINAYE
GFSNQAPPST AADSQGFYSA VHFDPMHGQS YRSYIHNYAV VGSGADCGQG STGAACPGVG
EGMDGYPPQT SEYRGATMTL GRLCRPLKKP KAKPPPPKRT SSLKEACGSG APESVLPEPS
DQAEPTTPLS GQSQTQTLNL PVSPRDREMR LQLDLTCPGQ AEVAGLEADV AVVSGGGGAW
GMGSPRSPRT VEMTEPTSFG STDTHSFKNE GAVQSDYADL WLLNDLKSKN SSDPYGSLSN
SSTATGTTVV ECIRSPVDTS SSPGGETRAL VHSSGSGSSS SRPASPPLPP GDGDFKLGSP
EKLAGLASPS SGYSSQSETP TSSFPSAFFP GPLSPNSGKR KPKVPERKSS LSSLQNQTHF
SSSASSSSSS SSTSSRKDYD FPAPPTQLDL SALHSGSHSS RPLPMLAHRT HMQTLHQNKQ
KAAAAAAAAA EARAANNAAA NANTSANANT SANANAMASA TSSGFSYGSA MTPEAPLAAN
PMALAITPTV LRSVQLRSTC QRAADSAQAQ SQGAQGQEPP PPPQAWTHEA RGAPATRPKM
PSVTIVTPHS DTNTRPLPPR RPIAQKPPPP QIQDHYQNLS QEQHPHSVTH QHPTPMQHPD
GPPPYESLAR HRQDRYGPGT FWAMTAFRTR LAEPMEPLEL EEPTHRAPPP TPEPIVPTTH
PECHVLGERT EDEEEDEDEE HDREISRVMS HSQGLMREYR ERNQREHPRE PPTYETLEES
HSYQSQSQYH SNTVRRCDLE PRGSPNKVPG TTAAASHPYP ISGLRGGSED DHEMTPFGVP
SRSASQDNSR GDSTTPETED YFSKDSTSPS DNSLSPMTDE TTKPDDDVVF TSPSKSRTTE
DLFAMIHRSK RKVLGRKDSG ELSGKSRLCP PPAAVVPPVA VLPAIPPPPP LNIPTGSTLS
PAGTQRTPGP IYRSAKKSST SNEEFKLLLL KKGSRTDSSY RMSATEILKS PIAPKSPGDP
LSADSQARYS TEDPSSPLQE PSLQGPGEQL FPPSLLPRTN SDSFSPKTLP MSASSRQGRS
RIPPAANSSR YSTRSRLYTA PMQAISEGET ENSDGSPHDD RSS
//
