ID A0A3P9AEZ7_ESOLU Unreviewed; 368 AA.
AC A0A3P9AEZ7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Developmentally regulated GTP binding protein 1 {ECO:0000313|Ensembl:ENSELUP00000039194.2};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000039194.2, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000039194.2, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000039194.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P9AEZ7; -.
DR STRING; 8010.ENSELUP00000039194; -.
DR Ensembl; ENSELUT00000041261.2; ENSELUP00000039194.2; ENSELUG00000019289.2.
DR GeneTree; ENSGT00940000153340; -.
DR InParanoid; A0A3P9AEZ7; -.
DR OMA; SAKHPGQ; -.
DR OrthoDB; 146471at2759; -.
DR Proteomes; UP000265140; LG14.
DR Bgee; ENSELUG00000019289; Expressed in embryo and 14 other cell types or tissues.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd01896; DRG; 1.
DR CDD; cd17230; TGS_DRG1; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 6.10.140.1070; -; 2.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR045001; DRG.
DR InterPro; IPR031167; G_OBG.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR031662; GTP-binding_2.
DR InterPro; IPR006074; GTP1-OBG_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR004095; TGS.
DR InterPro; IPR012676; TGS-like.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43127:SF1; DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR43127; DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2; 1.
DR Pfam; PF01926; MMR_HSR1; 1.
DR Pfam; PF16897; MMR_HSR1_Xtn; 1.
DR Pfam; PF02824; TGS; 1.
DR PRINTS; PR00326; GTP1OBG.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF81271; TGS-like; 1.
DR PROSITE; PS51710; G_OBG; 1.
DR PROSITE; PS00905; GTP1_OBG; 1.
DR PROSITE; PS51880; TGS; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140}.
FT DOMAIN 64..291
FT /note="OBG-type G"
FT /evidence="ECO:0000259|PROSITE:PS51710"
FT DOMAIN 291..367
FT /note="TGS"
FT /evidence="ECO:0000259|PROSITE:PS51880"
SQ SEQUENCE 368 AA; 40696 MW; F0B196723D5D0FC6 CRC64;
MSLLAKIAEI EAEMARTQKN KATSNHLGLL KARLAKMRRE LITPKGGSGG GAGEGFDVAK
TGDARIGFVG FPSVGKSTLL SNLAGVYSEV AAYEFTTLTT VPGVIRYKGA KIQLLDLPGI
IEGAKDGKGR GRQVIAVART CNLILIVLDV LKPLGHKKLI EHELEGFGIR LNKQPPNIGF
KKKDKGGINF TVTVNLFNSF TSSSVLKSIL AEYKIHNADI TLRSDCTADD LIDVVEGNRV
YIPCIYVLNK IDQISIEELD IIYKVPHCVP ISAHSRWNFD DLLEKMWDYL HLVRIYTKPK
GQLPDYTSPV VLPTDHTTVE DFCLKIHKSL LKELKYALVW GASVKHNPQK VGKDHVMEDE
DVIQLVKK
//
