ID A0A3P9AJP6_ESOLU Unreviewed; 805 AA.
AC A0A3P9AJP6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Scaffold attachment factor B2 {ECO:0000313|Ensembl:ENSELUP00000041346.2};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000041346.2, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000041346.2, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000041346.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3P9AJP6; -.
DR Ensembl; ENSELUT00000034453.2; ENSELUP00000041346.2; ENSELUG00000022327.2.
DR GeneTree; ENSGT00940000155916; -.
DR Proteomes; UP000265140; LG08.
DR Bgee; ENSELUG00000022327; Expressed in embryo and 15 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12679; RRM_SAFB1_SAFB2; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR034781; SAFB1_2_RBD.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR PANTHER; PTHR15683; SCAFFOLD ATTACHMENT FACTOR B-RELATED; 1.
DR PANTHER; PTHR15683:SF4; SCAFFOLD ATTACHMENT FACTOR B2; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS50800; SAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 23..57
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT DOMAIN 349..427
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 79..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 189..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 422..558
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 660..680
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 698..757
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 578..633
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 95..112
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..143
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..166
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 218..283
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 291..309
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 316..346
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 698..744
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 805 AA; 90969 MW; 5A5431ED822A579C CRC64;
MSENSSAGEA CAVEIPEGAI RKLSDLRVID LKAELKRRNL DATGIKSTLT ERLKKAIEEE
GGNPDEIVIG VDATPRKALA KRASKGKRPE NEELEDCTID EDSGDGQDDN IQDMDILDMN
VLDEAENDNG MAAEDEYDTD EVLNSPSDEG KPEIPDDEEE AMNEDEHDND IREAVREMCY
KNDKVAGSCL SEPLNEERLE PSTEEQATTG DAVNVAEEDN VCNSTKAEKA VNVETELSSS
EMDTDVAKLT ESQTNNSEDT QNVAEETVGA ESGNTQAVSV SEQGAGAVDS EMLSKDEEEG
KKTEENAAES TAVKESSSVE GDDQKKSSDE EKGSKPDSKD DKGESSGGKN LWVSGLSSTT
RATDLKTLFS KYGKVVGAKV VTNARSPGAR CYGFVTMCSS EEATKCISHL HRTELHGRMI
SVERAKNEPA GKKPADKSDV KRSGADRRHS SDSKSDEKAE GEVGKDGKRN ERTVVMDKSK
GEPVISVKAK SKDRSTKSRD RKSSSKEKKD ILSFDQIKEQ RERERQRQRE REIRETERRR
HSGERDRSSG DGRTERERIR LFREKEERER LLRKRNWLEV EKERLKFERM EREFLERERQ
RVEYERRREQ ERIQREREEL RRQQEQLRFE QERRPLKRPY DLDSRKDDWS DSKRIGLDDR
YGGRSDFGRP DRYQDIDHRD RGRYQDVSVI DRYRKGHFSD RAERPGKDTR DGWAPAGRYD
KRAINPRSPR DWDSGRKMDG DRVWPTGRDG GIPGQSHMGA RGGMANRGGY MATGTSQSLS
GALNRQNQMM QGSGMQGGGA FGRRY
//
