ID A0A3P9AJW8_ESOLU Unreviewed; 466 AA.
AC A0A3P9AJW8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Ankyrin repeat and SOCS box containing 10 {ECO:0000313|Ensembl:ENSELUP00000041338.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000041338.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000041338.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000041338.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_010884227.1; XM_010885925.2.
DR AlphaFoldDB; A0A3P9AJW8; -.
DR STRING; 8010.ENSELUP00000041338; -.
DR Ensembl; ENSELUT00000034464.2; ENSELUP00000041338.1; ENSELUG00000022169.2.
DR GeneID; 105019612; -.
DR KEGG; els:105019612; -.
DR GeneTree; ENSGT00940000158974; -.
DR InParanoid; A0A3P9AJW8; -.
DR OMA; ACVNNMD; -.
DR OrthoDB; 1787271at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000265140; LG03.
DR Bgee; ENSELUG00000022169; Expressed in muscle tissue and 4 other cell types or tissues.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03723; SOCS_ASB4_ASB18; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24203:SF83; ANKYRIN REPEAT AND SOCS BOX PROTEIN 15-RELATED; 1.
DR PANTHER; PTHR24203; ANKYRIN REPEAT FAMILY PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR SMART; SM00248; ANK; 6.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 5.
DR PROSITE; PS50088; ANK_REPEAT; 5.
DR PROSITE; PS50225; SOCS; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000265140}.
FT REPEAT 119..151
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 151..183
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 184..216
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 218..250
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 292..324
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 414..457
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 466 AA; 52631 MW; 04FED7E326523142 CRC64;
MSGRGSFVFT PAALRSLQLD EDMLERHKNK KQLSSDYMLK REARYRVGPG PVRSSIYVRP
PAMCHDLVIQ NALYTGDMDA VRRFFPKGIT SNVIIKPQGG DMRWVARAEG LWSLTYEQEL
TTPLHITSGR GYVDCLSHLL QRGASVDLAP GGITALHEAC QSCQPECVKL LLSYGANSNA
VSEEGLMPLH MCTRPESLEC AKYLLQFGAA INGRSLDEDN TPLHVAAQNG LLDHVEMYLR
YGATLDKQNY DNVTPLNAAC SQPQEKKDLE RYTKVCEMLL RAGAKVTTED LDNQSPLHMA
CKNVNPDMVD LLLARGACVN AMCYSGDTPM QNVLKMVAYK PDHKPEKVVR SLLNHGSLRV
WPEALPKVLQ YCSVSPRTIE VLLNAYDRLK ITDDWVKAIS PEMFMEHKGF YESLFSLQKT
PRSLQHLARW KLRNYLQGRV HKVVPQLDLP TFIKNYLLLD FRDHLH
//
