ID A0A3P9ANZ3_ESOLU Unreviewed; 380 AA.
AC A0A3P9ANZ3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Serpin B6 {ECO:0000256|ARBA:ARBA00039202};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000042808.2, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000042808.2, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000042808.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBUNIT: Forms a complex with the monomeric form of beta-tryptase.
CC {ECO:0000256|ARBA:ARBA00038828}.
CC -!- SIMILARITY: Belongs to the serpin family. Ov-serpin subfamily.
CC {ECO:0000256|ARBA:ARBA00006426}.
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DR RefSeq; XP_010883959.1; XM_010885657.3.
DR AlphaFoldDB; A0A3P9ANZ3; -.
DR STRING; 8010.ENSELUP00000042808; -.
DR Ensembl; ENSELUT00000037212.2; ENSELUP00000042808.2; ENSELUG00000001022.2.
DR GeneID; 105019450; -.
DR KEGG; els:105019450; -.
DR GeneTree; ENSGT00940000154835; -.
DR InParanoid; A0A3P9ANZ3; -.
DR OMA; HRAPANE; -.
DR OrthoDB; 3218836at2759; -.
DR Proteomes; UP000265140; LG21.
DR Bgee; ENSELUG00000001022; Expressed in nose and 9 other cell types or tissues.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd19956; serpinB; 1.
DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 1.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 1.
DR InterPro; IPR000240; Serpin_B9/Maspin.
DR InterPro; IPR023795; Serpin_CS.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR000215; Serpin_fam.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR InterPro; IPR042185; Serpin_sf_2.
DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1.
DR PANTHER; PTHR11461:SF204; SERPIN B6; 1.
DR Pfam; PF00079; Serpin; 1.
DR PRINTS; PR00676; MASPIN.
DR SMART; SM00093; SERPIN; 1.
DR SUPFAM; SSF56574; Serpins; 1.
DR PROSITE; PS00284; SERPIN; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140}.
FT DOMAIN 13..380
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
SQ SEQUENCE 380 AA; 43268 MW; 6E5CB71313E2C4D8 CRC64;
MESVSVANNE FSLELFKKIT EKNKTGNVFY SPLSISSALA MVSLGARGNT VTQMSESLHL
HKTKDDVHVG FSKLMSELNK EGTLYELRIA NRLYGEQSYQ FVKTFLHNTK KHYNAELEAV
DFKSNAETVR QNINTWVEKQ TAEKIKDVLP KGIVDQITRL ALVNAIYFKG NWEKKFSETR
TRDANFRLNK NDSKPVKMMY QKAEFPIMMI YEARSLVLEM PYEGNQLSML IMLPKDIEDD
TTGLEELEKQ LTYENFVQWT RPDYMNTVEV EVGLPKFKLE ESLDLKETLG SMGMIDAFDN
SRSDFSGMSP NNDLVLSKVV HKAFVEVNEE GTEAAAATAA IMAQNCALKI PPFIADHPFL
FFIRHNPTQS ILFSGRYSSP
//
