ID A0A3P9APM3_ESOLU Unreviewed; 523 AA.
AC A0A3P9APM3;
DT 02-DEC-2020, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=GATA binding protein 6 {ECO:0000313|Ensembl:ENSELUP00000042634.2};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000042634.2, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000042634.2, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000042634.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A3P9APM3; -.
DR Ensembl; ENSELUT00000036896.2; ENSELUP00000042634.2; ENSELUG00000023929.2.
DR GeneTree; ENSGT00940000160814; -.
DR InParanoid; A0A3P9APM3; -.
DR OMA; ENSMLHC; -.
DR Proteomes; UP000265140; LG03.
DR Bgee; ENSELUG00000023929; Expressed in heart and 10 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd00202; ZnF_GATA; 2.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 2.
DR InterPro; IPR008013; GATA_N.
DR InterPro; IPR039355; Transcription_factor_GATA.
DR InterPro; IPR000679; Znf_GATA.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR10071; TRANSCRIPTION FACTOR GATA FAMILY MEMBER; 1.
DR PANTHER; PTHR10071:SF23; TRANSCRIPTION FACTOR GATA-6; 1.
DR Pfam; PF00320; GATA; 2.
DR Pfam; PF05349; GATA-N; 1.
DR PRINTS; PR00619; GATAZNFINGER.
DR SMART; SM00401; ZnF_GATA; 2.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 2.
DR PROSITE; PS00344; GATA_ZN_FINGER_1; 2.
DR PROSITE; PS50114; GATA_ZN_FINGER_2; 2.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00094}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..523
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5028415579"
FT DOMAIN 317..371
FT /note="GATA-type"
FT /evidence="ECO:0000259|PROSITE:PS50114"
FT DOMAIN 371..424
FT /note="GATA-type"
FT /evidence="ECO:0000259|PROSITE:PS50114"
FT REGION 24..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 188..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 415..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..53
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 188..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..260
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 433..478
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 523 AA; 55943 MW; 0B6BC6B390154DFF CRC64;
IAPLFLLILY KLLSNSHWSM VKREVSSSPG SPAEQNYLHG GQDRRDSNSH AHDSEGLRSP
PPTDQLDSVG HRRTDGPGRS SLHSYVHFGH GHHNNNTALP TPEDITLFTD LDQGNKLIIS
SGAHPHHKGG LIVDPSDMYQ TLAIAAAHQS QASYDSSSGG YMHSNTNSPV YVPSSRVGPM
IPSLPYLQAS GSSQPSHAVT SHSVWSQSTP ESPSYSTGSP HTSNRFHYPP SPPMNNGAPR
DNGYSNLNVS SRDQYGLSRP LSGSYTSPYS PYVGPQLSQL SSPWPGGPFD NTMLHTLQSR
GAPLTIRGPN GDLLDDLGES RECVNCGSIS TPLWRRDGTG HFLCNACGLY SKMNGLSRPL
IKPQKRMSSS RRIGLSCANC QTSTTTLWRR NAEGEPVCNA CGLYTKLHGV PRPLAMKKEG
IQTRKRKPKT LNKTKGSSGN NSVPMTPTST SSSNSEDCSK NSSPNTQVQP SVLSGPVEGS
GSGGSAVVKY PGQDGLYTSV GLSQSVDVAV SVRGETWCPM ALA
//
