ID A0A3P9APY1_ESOLU Unreviewed; 662 AA.
AC A0A3P9APY1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Actin binding LIM protein 1b {ECO:0000313|Ensembl:ENSELUP00000042762.2};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000042762.2, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000042762.2, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000042762.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR AlphaFoldDB; A0A3P9APY1; -.
DR Ensembl; ENSELUT00000037150.2; ENSELUP00000042762.2; ENSELUG00000024195.2.
DR GeneTree; ENSGT00950000182850; -.
DR Proteomes; UP000265140; LG05.
DR Bgee; ENSELUG00000024195; Expressed in heart and 14 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR CDD; cd09327; LIM1_abLIM; 1.
DR CDD; cd09328; LIM2_abLIM; 1.
DR CDD; cd09329; LIM3_abLIM; 1.
DR CDD; cd09330; LIM4_abLIM; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 4.
DR Gene3D; 1.10.950.10; Villin headpiece domain; 1.
DR InterPro; IPR032402; AbLIM_anchor.
DR InterPro; IPR003128; Villin_headpiece.
DR InterPro; IPR036886; Villin_headpiece_dom_sf.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24213; ACTIN-BINDING LIM PROTEIN; 1.
DR PANTHER; PTHR24213:SF18; ACTIN-BINDING LIM PROTEIN 1; 1.
DR Pfam; PF16182; AbLIM_anchor; 1.
DR Pfam; PF00412; LIM; 4.
DR Pfam; PF02209; VHP; 1.
DR SMART; SM00132; LIM; 4.
DR SMART; SM00153; VHP; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 6.
DR SUPFAM; SSF47050; VHP, Villin headpiece domain; 1.
DR PROSITE; PS51089; HP; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 3.
DR PROSITE; PS50023; LIM_DOMAIN_2; 3.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 5..64
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 65..124
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 132..191
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 594..662
FT /note="HP"
FT /evidence="ECO:0000259|PROSITE:PS51089"
FT REGION 250..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 372..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 662 AA; 73880 MW; 62D5158008D77CC0 CRC64;
VKLVIQCYKC GESCKGEVLR VQSKHFHLKC FTCKVCGCDL AQGGFFMKNG DYLCTLDYQR
LHGTRCNGCG DFVEGEVVTA LGKTYHPACF VCTICKRPFP AGDRVTFNGK DCLCQRCIQP
LSPTPKDVSS SSNCAGCGRD IKNGQALLAL DRQWHLGCFK CNACGKVLSG EYISKDGAPY
CEKDYQIHFG VQCEACNQFI TGKVLEAGDK HYHPSCARCS RCNQMFTEGE EMYLQGSTVW
HPDCKNNSRA EEKYRPTRSS SESICSRPGS SIPGSPGHTI YAKVDNEIID YRDLAAIPRV
KAIYDIERPD MISYATLHSN SSTLDHRADR QDRHSPAEVT ALGGANSPRT LSPTPSAEGC
YDTRDRIIMQ RSTSQGSIGS PATYNRHNYT PTLSRSPQHF HRPGTDPSSN RSSPLSWPVT
PTLSLTPKHY HIPGRSRRGQ MQLVYSAAMA AQSKSADAII KSAKFPAAHA PGLDEKPKIE
TVYWPCPPSL AALGRILLLT APGHLNCEQI NRFHVLCYTL KKILNELQLC SQFLLSWTAI
RSVCKFVLCS SDPNSPTCKT SSLPGYGRNG LHRPMQDGQR PSARMDRGVS MPNMLEPKVF
PYELLTITNR GRAKFPRDVD RTRLERHLAP ELFFDIFGME IQEFDRLPLW KRNDMKKKAK
LF
//
