ID   A0A3P9AS77_9CICH        Unreviewed;       908 AA.
AC   A0A3P9AS77;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
OS   Maylandia zebra (zebra mbuna).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX   NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005000526.1, ECO:0000313|Proteomes:UP000265160};
RN   [1] {ECO:0000313|Ensembl:ENSMZEP00005000526.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P9AS77; -.
DR   Ensembl; ENSMZET00005000591.1; ENSMZEP00005000526.1; ENSMZEG00005000481.1.
DR   GeneTree; ENSGT01100000263487; -.
DR   Proteomes; UP000265160; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF13516; LRR_6; 2.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   SMART; SM01288; FISNA; 1.
DR   SMART; SM00368; LRR_RI; 6.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS51450; LRR; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265160}.
FT   DOMAIN          79..213
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   908 AA;  102814 MW;  06A801ACD0551664 CRC64;
     RDCRKPTCVL EGISTTENPT LLSQIYTELY ITGGGTAEVN DEHEVRQIET ASRKPDRPET
     TIRQEDIFKL PPGRDKPIRT VLTMGVAGIG KTVLTQKFTL DWAEGKANQD IQFMFPFTFR
     ELNLLKEDKF SLVELVHHFF TETKEAGIYI FEDFQVVFIF DGLDECRPPL DFHKTAILTD
     PRKSTSVDVL LINLIRGKLL PSARLWITTR PAAANKILCD IVDMVTEVRG FTDPQKEEYF
     RKRFRDEEQA SSIISHIKTS RSLHIMCHIP VFCWITATVL EFVMKNKESK DLPKTLTELY
     LRLVLFHLKT KDIKYDGEAE TDSCRKIIES LGKLAFDQLQ KGNLIFYKSD LTECGIDIRA
     ASVYSGVFTQ IFKADECHMF NNVVYCFVHL SIQEFFAALH VYLTFINSGV NLLKKQSPRF
     KIFQKTLTVK DFYQSAVDKA LESPNGHLDL FLRFLLGLSL QTNQDLLCML TETGSSSQTN
     QETVQYIKKK LSGKLSAEKS INLFHCLNEL DDRSLVEEIQ QSLRSGRLST DQLSPAQWSA
     LVFILLSSDL DEFNLKKYSR SEKAFLKLLP NMSPLLFFLR LRDCKLSKRS FEALSEILSS
     PSNHLRELDL SSNKLQDSGL DLLCVGLKSP DCKLETLSTL CAGYLACGLS EISCDYLAAA
     LKSNPSHLRQ LDLSTDYSWL STNNNNLQDP GVKHLCGFLE SPGCKLETLR SVSILEGCGL
     SDIGLEYLAA ALKSNPSYPT EVDLSGTYSN LQDPGVKHLC GFLENPRCKL ETLRLRNCGL
     SEISCDYLVA ALKSNPSHLR QLDLSDNDKL QDPGVKHLCG FLESPGCKLE TLRVFKINTI
     QYCGRSFIEL RSKNKSQNEV AALCFTSIIE VLRQLNPHCT LSTLFSDRHE HFHTFLSCLN
     KVQTFIEK
//