ID A0A3P9ATL7_9CICH Unreviewed; 325 AA.
AC A0A3P9ATL7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Protein prune homolog 2 {ECO:0000256|ARBA:ARBA00039860};
DE AltName: Full=BNIP2 motif-containing molecule at the C-terminal region 1 {ECO:0000256|ARBA:ARBA00042084};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005001039.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005001039.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005001039.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_004549787.1; XM_004549730.2.
DR RefSeq; XP_004549788.1; XM_004549731.1.
DR RefSeq; XP_004549789.1; XM_004549732.1.
DR AlphaFoldDB; A0A3P9ATL7; -.
DR Ensembl; ENSMZET00005001122.1; ENSMZEP00005001039.1; ENSMZEG00005000859.1.
DR GeneID; 101474106; -.
DR KEGG; mze:101474106; -.
DR CTD; 158471; -.
DR GeneTree; ENSGT00940000161347; -.
DR OrthoDB; 5402707at2759; -.
DR Proteomes; UP000265160; LG7.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR InterPro; IPR022181; Bcl2-/adenovirus-E1B.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR PANTHER; PTHR12112; BNIP - RELATED; 1.
DR PANTHER; PTHR12112:SF11; PROTEIN PRUNE HOMOLOG 2; 1.
DR Pfam; PF12496; BNIP2; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160}.
FT DOMAIN 134..291
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
FT REGION 1..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 299..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 325 AA; 36740 MW; D3556B932171D175 CRC64;
MDLASGSKMN SEGDDGRPVP PTSLPLQGGA SQRKKLSAPR ISLSLDQSED DFGETPDDLD
INVDDLDTPD EGDYLDYTDH EMDWEDPNTA NRSATSEVYN TIPTYSAEEE RQDGKLWRTV
IIGEQEHRIN MKLIEPYMKV ISHGGYYGNG VNAIIVFAAC FLPDSDREEY HEIMENLFLY
VISTLELMVA EDYMIVYLNG ATPHRRMPGL GWLKKCYQMI DRRLRKNLKS FIILHPSWFI
RTILAITKPF ISTKFSSKIK YVNSLDELQE LIPMDCIQIP ECIIRLDKQL KEAAENSRVN
SFLQGSEPTA ASRTDRPDAA GASGS
//
