ID A0A3P9AU59_9CICH Unreviewed; 898 AA.
AC A0A3P9AU59;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=ARVCF delta catenin family member {ECO:0000313|Ensembl:ENSMZEP00005001153.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005001153.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005001153.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005001153.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the beta-catenin family.
CC {ECO:0000256|ARBA:ARBA00005462}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3P9AU59; -.
DR Ensembl; ENSMZET00005001241.1; ENSMZEP00005001153.1; ENSMZEG00005000889.1.
DR GeneTree; ENSGT00940000157027; -.
DR Proteomes; UP000265160; LG12.
DR GO; GO:0098609; P:cell-cell adhesion; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR028435; Plakophilin/d_Catenin.
DR PANTHER; PTHR10372:SF5; ARMADILLO REPEAT PROTEIN DELETED IN VELO-CARDIO-FACIAL SYNDROME; 1.
DR PANTHER; PTHR10372; PLAKOPHILLIN-RELATED; 1.
DR Pfam; PF00514; Arm; 4.
DR SMART; SM00185; ARM; 6.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 3.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160}.
FT REPEAT 377..414
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 420..463
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 680..717
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 1..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 75..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 197..278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 311..331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 568..618
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 829..898
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..237
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..278
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 583..618
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 869..898
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 898 AA; 100336 MW; 5AC3091FFD65B081 CRC64;
MPAEVKQEQS PSNATSLAMM QEPQEVVEET VTIEEDPGTP TSHVSVVTSD DGTTRRTETK
VTKMVKTVTT RTVRQVPLGP DGLPLPEGTS PLGSYTDSID RRYLKNGSDR FITPQATSTL
TRSYNNSYND SYGETPESQY IRHYGLHDGY TDLTDNYGSL SRGVNYRPPR YPYMPNSYRP
ENSYTLPIRK DDYGHVAQPQ VPMGSSTVDL NRSQPERFQP EPYGLEDDRR SLGPEEEEPY
ELEADYSTAN RRTLPGANRG RTHREPLRDG PRVRGYPDDP IEAELIDERH PYIHGMYSAP
LAQPERGSMA SLDRMGGRRS PSIDSIRKDP RWRDPDLPEV IAMLGHPIDP VKSNAAAYLQ
HLCYENDKIK KDVRQLKGIP VLVGLLDHPK SEVHRKACGA LRNISYGKDN DNKVAIKNCD
GIPALIRLLR KTNDMEVREL ITGTLWNLSS YEPLKMVIIN HGLQTLTNEV IIPHSGWEHE
PNEDSKPRDA EWTTVFKNTS GCLRNVSSDG AEARRRLREC EGLVDALLHA LQSAVGKKDM
DNKSVENCVC IMRNLSYHVH KEVPGAEKYQ DPSALQAPGS AGPQRKKKDD AGCFGGKKAK
GRKNGENDKS YDTLDLPKRT EPSKGFELLY QPEVVRLYLS LLTESQNYNT LEAAAGALQN
LSAGQWTWSS YIRATVRKEK GLPILVELLR SDSDKVVRAV AIALRNLSID RRNKDLIGSY
AMRDLVSNLP SGQQRPAKNL EEDTVVAILN TIHEIVTDSS ENARSLIQAQ AIEKLVAINR
TSQSARETKA ASHVLQTVWS YKELRNALAK DGWNKSHFQL TVTATPKATK NGKPGYDDTT
LPLMEKNQGT RKCGSGDMIP MDELGPDGYS TIDQRDKDCK YKTGDGSVDL TEREPLKA
//
