ID A0A3P9AY06_9CICH Unreviewed; 631 AA.
AC A0A3P9AY06;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=FAST kinase domain-containing protein 3, mitochondrial {ECO:0000313|Ensembl:ENSMZEP00005002529.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005002529.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005002529.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005002529.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_004566084.1; XM_004566027.3.
DR AlphaFoldDB; A0A3P9AY06; -.
DR STRING; 106582.ENSMZEP00005002529; -.
DR Ensembl; ENSMZET00005002642.1; ENSMZEP00005002529.1; ENSMZEG00005002006.1.
DR GeneID; 101474447; -.
DR KEGG; mze:101474447; -.
DR GeneTree; ENSGT01030000234607; -.
DR OrthoDB; 4051655at2759; -.
DR Proteomes; UP000265160; LG16.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR GO; GO:0044528; P:regulation of mitochondrial mRNA stability; IEA:InterPro.
DR InterPro; IPR013579; FAST_2.
DR InterPro; IPR010622; FAST_Leu-rich.
DR InterPro; IPR013584; RAP.
DR PANTHER; PTHR21228:SF9; FAST KINASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL; 1.
DR PANTHER; PTHR21228; FAST LEU-RICH DOMAIN-CONTAINING; 1.
DR Pfam; PF06743; FAST_1; 1.
DR Pfam; PF08368; FAST_2; 1.
DR Pfam; PF08373; RAP; 1.
DR SMART; SM00952; RAP; 1.
DR PROSITE; PS51286; RAP; 1.
PE 4: Predicted;
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..631
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017947582"
FT DOMAIN 545..603
FT /note="RAP"
FT /evidence="ECO:0000259|PROSITE:PS51286"
FT REGION 62..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 631 AA; 71318 MW; 4F5490B1004AF2AE CRC64;
MKSLMCLLAS VRAASPFPLN CGSVRKRTSV EFGSNTARCL QITRGTDLKL MSEAAVPLLR
KRDTGPSWDR TGRRTAPQKA PGAALSPYIP YTKPQSKAAA LFDIQSLFEE DVIAELCSRL
QAFPRSDRAE GLASLLGACV EFGLEAHSPP VLTLMNECLE LLSNRDIGVA QLCRLGEVVC
ALEGRRSRVL TEVLDCVCAA VEEDVVSPSE AVMVYSLLTR FCEPASQQQT RILSALHTDT
RRLVHRLKAG QVSDILQSLL KLQQTQAVSL VLRLSHRASR VFKAFRDDEI MKVLTALMTL
EQHDGELVAA MEKHLPGRLE KCDPELIGAI VEYCVQMRCR SEPLFEAVAE NFVRHAENHT
TLQIAKQIVA MGRLNYLPQC SSQMFKKLES ILSERFSQFQ PRSLVDVMHA CIHLERFPLN
YMTKVFSPHF LQKLQAQGEP LDKNTLGQLT QLHLSTMLEC TYYWGPRLPF FLHVKRFSSA
GQAFETPMER LLYKQVKGPL AQLLGGTFYS TRMIHGGYTI DVEICLDESG FVLPPSQWDH
TYKRVVLCLD DPNRFCTNTR HLLGKEVTKR RHLQRMGVEL VEIPYFEFEK LQTEEEQIQY
LHDKIFPAVS KFNNQAANQL NQKSTVRQTS L
//
