ID A0A3P9B2Z9_9CICH Unreviewed; 390 AA.
AC A0A3P9B2Z9;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Thyrotroph embryonic factor {ECO:0000313|Ensembl:ENSMZEP00005004288.1};
GN Name=TEF {ECO:0000313|Ensembl:ENSMZEP00005004288.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005004288.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005004288.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the bZIP family. PAR subfamily.
CC {ECO:0000256|ARBA:ARBA00009208}.
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DR RefSeq; XP_004575559.1; XM_004575502.2.
DR AlphaFoldDB; A0A3P9B2Z9; -.
DR STRING; 106582.ENSMZEP00005004288; -.
DR Ensembl; ENSMZET00005004469.1; ENSMZEP00005004288.1; ENSMZEG00005003328.1.
DR GeneID; 101481452; -.
DR KEGG; mze:101481452; -.
DR CTD; 553686; -.
DR GeneTree; ENSGT00940000156578; -.
DR OrthoDB; 5354784at2759; -.
DR Proteomes; UP000265160; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd14695; bZIP_HLF; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR InterPro; IPR040223; PAR_bZIP.
DR PANTHER; PTHR11988:SF47; TEF TRANSCRIPTION FACTOR, PAR BZIP FAMILY MEMBER B; 1.
DR PANTHER; PTHR11988; THYROTROPH EMBRYONIC FACTOR RELATED; 1.
DR Pfam; PF07716; bZIP_2; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR PROSITE; PS50217; BZIP; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160}.
FT DOMAIN 320..383
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT REGION 80..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 162..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 317..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..197
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..235
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..256
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 390 AA; 42901 MW; 53A8C1CCB706C3FD CRC64;
MQSARSRFVG VNKSCVFEQS GQFHKLSNMT AANQMFFEDR SDVPDLLRYL ADCPFPAFDD
SEIEKEKLCS SEDVDGGGAV ANNAGGGSRG GGGGSGGSGG VSASLTPAIW EKTIPYDGET
FHLEYMDLDE FLLENGIPVT LEEEELQKTL TVEDKGKAIP KAIAGATTTT PTPTTTETTT
PATPVAADSS SPPSASMATP DPEEPVTVTT LQPAKLEEEQ EEEEEEGEKE EEQKEESLPE
EATPKAEVKK AERNTPSPID PDAIEVDINF QPDPTDLVLS SVPGGELFNP RKHRFSQEEL
KPQPMIKKAK KVFVPDEQKD EKYWSRRKKN NLAAKRSRDA RRLKENQITV RASFLERENA
ALRQQVAEMR KDCGRCKNVL ARYEAKYGPL
//
