ID   A0A3P9BGG3_9CICH        Unreviewed;       691 AA.
AC   A0A3P9BGG3;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Double-stranded RNA-specific editase B2 {ECO:0000313|Ensembl:ENSMZEP00005008978.1};
GN   Name=ADARB2 {ECO:0000313|Ensembl:ENSMZEP00005008978.1};
OS   Maylandia zebra (zebra mbuna).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX   NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005008978.1, ECO:0000313|Proteomes:UP000265160};
RN   [1] {ECO:0000313|Ensembl:ENSMZEP00005008978.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P9BGG3; -.
DR   Ensembl; ENSMZET00005009322.1; ENSMZEP00005008978.1; ENSMZEG00005006722.1.
DR   GeneTree; ENSGT00940000157252; -.
DR   Proteomes; UP000265160; Unplaced.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   Gene3D; 3.30.160.20; -; 2.
DR   InterPro; IPR002466; A_deamin.
DR   InterPro; IPR014720; dsRBD_dom.
DR   PANTHER; PTHR10910:SF17; DOUBLE-STRANDED RNA-SPECIFIC EDITASE B2; 1.
DR   PANTHER; PTHR10910; EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN; 1.
DR   Pfam; PF02137; A_deamin; 1.
DR   Pfam; PF00035; dsrm; 2.
DR   SMART; SM00552; ADEAMc; 1.
DR   SMART; SM00358; DSRM; 2.
DR   SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR   PROSITE; PS50141; A_DEAMIN_EDITASE; 1.
DR   PROSITE; PS50137; DS_RBD; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265160};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT   DOMAIN          90..156
FT                   /note="DRBM"
FT                   /evidence="ECO:0000259|PROSITE:PS50137"
FT   DOMAIN          249..313
FT                   /note="DRBM"
FT                   /evidence="ECO:0000259|PROSITE:PS50137"
FT   DOMAIN          362..682
FT                   /note="A to I editase"
FT                   /evidence="ECO:0000259|PROSITE:PS50141"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   691 AA;  76397 MW;  EA9239094630F57E CRC64;
     SPIKHWDTEA SSAEDADSSS TSSLEVKENQ DDKCQVERDL LRKYHPSTFC TTFPRNGQRA
     LKRKQPLVDG KDQLLYQSHS TCKRAAWGVT QKNALVHLNE LRPGLQYDIT SKTGPLHAPV
     FSVAVEVNGF HFEGRGPTKK QAKMRAAEQA LQSFIQFPNA SQAHATMGNF TSTPVDFTAD
     KVDIPNGFFK EFEPSVLRNC DLLHCNAAKK EVFSSIYNHR RLVRLTLDLV SSTNPKRRAV
     TTSLLEDLSP VALLNELRPG LRYMCLTERV PGRPMKTFVM VVRLEGRVFE GCAPSKRLAK
     ARAAATALQS LYNISLGPER TFMVCILPLA DSCSSTSHAR HKVLAGIVMT RGLDLRSAQV
     VSLATGTKCL DLGGVSDCGC TLTDCHAEVV SRRALVRFLY SQLELLLCKP VDSENQSIFI
     PNKNCGDGFR LREGVHFHMY VSSSPCGDAR LNCPYETTAA YPSRRFRCHL RVKVKGGEGT
     LPITARRANQ KWDGLSPSKP LVTMSCTDKL AKWSVVGLQG ALLSHLVEPV YLQSLTVGTL
     SHTGHLGRAM ARRLAPIKHL PFPYRRQQLL SRDARPAGKP PNVSVNWSCG DGGWEEISTS
     TGRRKDSGTP SRLCRRSLFA RWLRLQQQLI NPVIGAESTT GTYCASKMSA QCYQRAVQQF
     SSALQGGGLG TWLRKPPKLG HFTVSVSKTE R
//