ID A0A3P9BH35_9CICH Unreviewed; 707 AA.
AC A0A3P9BH35;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=VWFA domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005009220.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005009220.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005009220.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3P9BH35; -.
DR STRING; 106582.ENSMZEP00005009220; -.
DR Ensembl; ENSMZET00005009570.1; ENSMZEP00005009220.1; ENSMZEG00005006951.1.
DR GeneTree; ENSGT00940000162662; -.
DR Proteomes; UP000265160; LG14.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR013694; VIT.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR45737; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A; 1.
DR PANTHER; PTHR45737:SF8; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A; 1.
DR Pfam; PF13768; VWA_3; 1.
DR SMART; SM00609; VIT; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS51468; VIT; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160}.
FT DOMAIN 1..104
FT /note="VIT"
FT /evidence="ECO:0000259|PROSITE:PS51468"
FT DOMAIN 253..427
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT COILED 312..339
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 707 AA; 77618 MW; BBEBDC5BF726337B CRC64;
MVCIYSNIIF LSVPLKSIEV ELEVRDHVAT VVSTLNYENK EDKPLEAVLS SLCELDSKYN
LIISDSGQQA FLLEESDESP DIFSLRVGSL PPAESASIRL EYVTELAVQA DDSLRFCLPA
VSQILQASAS SEGASVQVTS VPASLVPYSL SFSARVSSPR PVSKVESNCS LDPLQYLNTD
QTQATVKLAA GHKFDRDVEL LIYYKDAHQP TAVVEAGQAS AEPGSLMGDP VVMVSLYPEF
PQSVMSSTAS CGEFVFLVDR SGSMDCATNN TEQQETRISS AKVFMMWSYQ WGCYFNIYSF
GSSYEHIFPK SVEYGEKTME EALKKVEQME ADLGGTEILE PLKHIYSQPC IPTQPRQLFV
FTDGEVGNTK EVIDLVKKNS GSHRCFSFGI GEGASSALIN GMAKEGGGHA QFITGTDRMQ
PKVMQSLRFA LQPAVEDVSV TWDLPKGSTV TVLSPPITAI FQGKRSLIYA QLTGQAAEGC
VTVKYSLAGH PSENQLHFSL RPAEDTGLIV HRLAARTLIC LLEMEAENNE EKEEVKKKVV
QLSVQSGVSS SFTAFIAVNK DNNKEIQGPL LHRDIPTLPD EEFPPAKKPP RDPLLQLVSL
QKASGCWLLD PALAAALGKT NEEVEKSNSE VWATILALIW LHGFKMDAKD EWELLAAKAV
SWLSAQKGSK HKNKHSVCDG YTELLQSLRL MLTEHFYSQY KASCCTV
//
