ID A0A3P9BJG8_9CICH Unreviewed; 112 AA.
AC A0A3P9BJG8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Eukaryotic translation initiation factor 4E-binding protein 3-like {ECO:0000313|Ensembl:ENSMZEP00005010099.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005010099.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005010099.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005010099.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eIF4E-binding protein family.
CC {ECO:0000256|ARBA:ARBA00005480}.
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DR RefSeq; XP_014267538.1; XM_014412052.1.
DR AlphaFoldDB; A0A3P9BJG8; -.
DR STRING; 106582.ENSMZEP00005010099; -.
DR Ensembl; ENSMZET00005010467.1; ENSMZEP00005010099.1; ENSMZEG00005007636.1.
DR GeneID; 101471035; -.
DR KEGG; mze:101471035; -.
DR CTD; 324490; -.
DR GeneTree; ENSGT00940000163328; -.
DR OrthoDB; 2911937at2759; -.
DR Proteomes; UP000265160; LG2.
DR GO; GO:0008190; F:eukaryotic initiation factor 4E binding; IEA:InterPro.
DR GO; GO:0045947; P:negative regulation of translational initiation; IEA:InterPro.
DR GO; GO:0014743; P:regulation of muscle hypertrophy; IEA:Ensembl.
DR InterPro; IPR008606; EIF4EBP.
DR PANTHER; PTHR12669; EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN; 1.
DR PANTHER; PTHR12669:SF5; EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 3; 1.
DR Pfam; PF05456; eIF_4EBP; 1.
PE 3: Inferred from homology;
KW Protein synthesis inhibitor {ECO:0000256|ARBA:ARBA00023193};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT REGION 81..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..112
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 112 AA; 12508 MW; C764DB01D7924BAA CRC64;
MSVDANQVKS RPIPTRVLTL KDWSQLPDCY SQTPGGTLFS TTPGGTRIIY DRKFLLDCRN
SPLARTPPCC LPQIPGVTVP ATHSTGKLQD LKEEEEEEEK DIADDNQFEM DI
//
