ID A0A3P9BKD1_9CICH Unreviewed; 446 AA.
AC A0A3P9BKD1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=RILP-like protein 1 {ECO:0000256|ARBA:ARBA00040816};
DE AltName: Full=Rab-interacting lysosomal-like protein 1 {ECO:0000256|ARBA:ARBA00042424};
GN Name=RILPL1 {ECO:0000313|Ensembl:ENSMZEP00005010385.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005010385.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005010385.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005010385.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the RILPL family.
CC {ECO:0000256|ARBA:ARBA00038318}.
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DR AlphaFoldDB; A0A3P9BKD1; -.
DR Ensembl; ENSMZET00005010756.1; ENSMZEP00005010385.1; ENSMZEG00005007818.1.
DR GeneTree; ENSGT00940000157897; -.
DR Proteomes; UP000265160; LG7.
DR GO; GO:0005929; C:cilium; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd14445; RILP-like; 1.
DR Gene3D; 1.20.58.1770; -; 1.
DR Gene3D; 6.10.230.10; -; 1.
DR InterPro; IPR019143; JNK/Rab-associated_protein-1_N.
DR InterPro; IPR034743; RH1.
DR InterPro; IPR034744; RH2.
DR InterPro; IPR021563; RILP_dimer.
DR PANTHER; PTHR21502:SF6; RILP-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR21502; ZINC FINGER PROTEIN DZIP1; 1.
DR Pfam; PF09744; Jnk-SapK_ap_N; 1.
DR Pfam; PF11461; RILP; 1.
DR SUPFAM; SSF161256; RILP dimerisation region; 1.
DR PROSITE; PS51776; RH1; 1.
DR PROSITE; PS51777; RH2; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 3..97
FT /note="RH1"
FT /evidence="ECO:0000259|PROSITE:PS51776"
FT DOMAIN 334..403
FT /note="RH2"
FT /evidence="ECO:0000259|PROSITE:PS51777"
FT REGION 369..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 409..429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 102..189
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 375..397
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 446 AA; 50671 MW; D658CFA4EF2EAD34 CRC64;
MEDFGSALEK NVADLTVMDV YDIAAVVGQE FERIIDQYGC EALSRLMPKV VRVLEILEVM
VSRSSISPET EELRLELDKL RLERIDRLEK EKKHRKELEL VEDVWRGEAQ DLLSQIAQLQ
EENKTLLTNM SMKDPMSEEE LQRHEGMSER ERQVMKKLKE VVDKQRDEIR AKDRELTLKN
EDIEALQQQQ SRLMKINHDL RHKISVVEAQ GKALIEQKVE LEASAQARGQ EVAALRQEAA
RLRERLQGEL PAQNPDEPPP QPPSPAECGK IATVLVGAEG SSELTPGGVD GVSWHLCGSL
SPETHEDAED DAVLLWEALC EEESGGLDPK DPNRPRFTLQ ELRDVLHERN ELKAKVFLLQ
EELAYYKSDE ADEEIGTPSS SPSPELRTRS RSSAQPESGI KRLFSFFSRD KQRSSQRSAH
FDVGFGSWAG KDDVYTEQAQ EALQHM
//
