ID A0A3P9BLK6_9CICH Unreviewed; 502 AA.
AC A0A3P9BLK6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Bridging integrator 2 {ECO:0000313|Ensembl:ENSMZEP00005010536.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005010536.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005010536.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005010536.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P9BLK6; -.
DR Ensembl; ENSMZET00005010908.1; ENSMZEP00005010536.1; ENSMZEG00005007927.1.
DR GeneTree; ENSGT00950000182882; -.
DR Proteomes; UP000265160; LG5.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR003005; Amphiphysin.
DR InterPro; IPR004148; BAR_dom.
DR PANTHER; PTHR46514; AMPHIPHYSIN; 1.
DR PANTHER; PTHR46514:SF1; BRIDGING INTEGRATOR 2; 1.
DR Pfam; PF03114; BAR; 1.
DR PRINTS; PR01251; AMPHIPHYSIN.
DR SMART; SM00721; BAR; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR PROSITE; PS51021; BAR; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160}.
FT DOMAIN 32..248
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT REGION 280..462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 478..502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 160..194
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 290..366
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 395..409
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 502 AA; 55440 MW; F888075CD4FD214D CRC64;
MAENKMGPNL QAGAGIFAKR VQKSLNRAQE KVLQKLGKTM ETKDEQFELC SQNLNKQQID
GSRLFKDVKA YYAAVKGMHE TSKRLSQTLS DIYESDWDGV KDLAVITESE DLLWNDYEEK
INDQLVRTME NYTSQFPEVK ERVAKRGRKL VDYDSARHHL EALQGAKKKD EAKIAKAEEE
FNKAQNVFEE INNELREELP VLHQSRIGCY VTVFENISNL RDVFYKEMSG LNRELYNVMK
KLETQHSGKA FIIKGLNSSK SKKRKSLVIS NPIPCNTAFP ADHVSVHSQN GKGAAPSSPV
PKTQNIAEES IPAEESSIPS KSVSSSDSDL SSSGTGSPKR QSLCDNDNSD TSSQNPEAAV
ASEPAESQSE DSKEGEPKSE AAASQEITDP SDSAGGDAPH KDAESDPTSE EANTKPAPVP
APRVSFRSNE SPLLPAKEQE DLDEGLESGD DSGSPSPPGF LYKVHEEGVV RGVREQSWNE
HQDAENHSGI FSEKLIRPIK EE
//
