ID A0A3P9BLW4_9CICH Unreviewed; 320 AA.
AC A0A3P9BLW4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Transposase Tc1-like domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005010919.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005010919.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005010919.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P9BLW4; -.
DR STRING; 106582.ENSMZEP00005010919; -.
DR Ensembl; ENSMZET00005011297.1; ENSMZEP00005010919.1; ENSMZEG00005008198.1.
DR GeneTree; ENSGT01100000263576; -.
DR Proteomes; UP000265160; LG19.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0006313; P:DNA transposition; IEA:InterPro.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR038717; Tc1-like_DDE_dom.
DR InterPro; IPR047655; Transpos_IS630-like.
DR InterPro; IPR002492; Transposase_Tc1-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; NF033545; transpos_IS630; 1.
DR PANTHER; PTHR23022:SF138; TRANSPOSABLE ELEMENT TC3 TRANSPOSASE; 1.
DR PANTHER; PTHR23022; TRANSPOSABLE ELEMENT-RELATED; 1.
DR Pfam; PF13358; DDE_3; 1.
DR Pfam; PF01498; HTH_Tnp_Tc3_2; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265160};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464}.
FT DOMAIN 72..140
FT /note="Transposase Tc1-like"
FT /evidence="ECO:0000259|Pfam:PF01498"
FT DOMAIN 150..301
FT /note="Tc1-like transposase DDE"
FT /evidence="ECO:0000259|Pfam:PF13358"
SQ SEQUENCE 320 AA; 37232 MW; 6EC7C3E27FAFA2FB CRC64;
MMGKSKELSQ DLRNLIVEKH FDGNGYRCIS RMLNVPVSTV GAIIRKWKVH QFTINLPRSG
APRKIPVRGV QRIIRRVLQE PRTTRTELQE DLASAGTVVS KKTISNALNR HGIHARSPRK
TPLLNKKHVK AQLKFAQQHL EKPVDYWTTI VWSDESKIEL FGSHSTHHVW RRNGTAHHPK
NTIPTVKFGG GSIMVWGCFS ARGTGRLHII EGRMNGEMYR DILDKNLLPS TRKLKMKRGW
TFQQDNDPKH KAKETMKWFQ RKKIKLLEWP SQSPDLNPIE NLWRELKIKV HKRGPRNLQD
LKTVCVEEWA RITPEQCRRL
//
