ID A0A3P9BNM3_9CICH Unreviewed; 631 AA.
AC A0A3P9BNM3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Dynein cytoplasmic 1 intermediate chain 1 {ECO:0000313|Ensembl:ENSMZEP00005011535.1};
GN Name=DYNC1I1 {ECO:0000313|Ensembl:ENSMZEP00005011535.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005011535.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005011535.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005011535.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the dynein intermediate chain family.
CC {ECO:0000256|ARBA:ARBA00011059}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_012773742.1; XM_012918288.2.
DR AlphaFoldDB; A0A3P9BNM3; -.
DR Ensembl; ENSMZET00005011936.1; ENSMZEP00005011535.1; ENSMZEG00005008570.1.
DR GeneID; 101481244; -.
DR CTD; 1780; -.
DR GeneTree; ENSGT00940000156032; -.
DR OrthoDB; 654577at2759; -.
DR Proteomes; UP000265160; LG22.
DR GO; GO:0005868; C:cytoplasmic dynein complex; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR025956; DYNC1I1/DYNC1I2.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR12442:SF34; CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN 1; 1.
DR PANTHER; PTHR12442; DYNEIN INTERMEDIATE CHAIN; 1.
DR Pfam; PF11540; Dynein_IC2; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000265160};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 466..513
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 147..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..61
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..100
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..174
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..192
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 631 AA; 70595 MW; 834167EAAF7160B3 CRC64;
MSDKSDLKAE LERKKQRLAQ IREEKKRKEE ERKKKETESQ QKTEATPEDS DLDRKRRETE
ALLQSIGISP EPPLVPTPVS PSKSVSTPSE TGSQDSADGG AAGRTLQWDT DPSVLQLQAD
SELGRRMQRL GASKITQVDF LPKEVVSYSK ETQTPTCTLS EVEEEEEDEE LMETKPGPES
EQQDEDDNRE AKEGSFPVLR ELTEEERQQI LHSSEFQSFF DCSIRVMERA LAEDSDIFFD
YSGRDLDDKE GDLGSGSSLS FSRLFYDEHW SKHRVITCLD WSPQYPELLV ASYNNNEDAP
HEPDGVALVW NIKFKKATPE YIFHCQSPVV SVGFARFHPN LVVGGTYSGQ IVLWDNRSHR
RTPVQRTPLS AAAHTHPVYC VNVVGTQNAN NLITVSTDGR MCSWSLDMLS QPQETMELVY
NKSKPVAVTC MAFPTGDVNN YVVGSEEGTV YTASRHGSKA GICEMFEGHQ GPVTGISCHS
AVGTVDFSHL FITSSFDWTV KLWSTKHNKP LYSFEDNADY VYDVMWSPVH PAMFAAVDGM
GRLDLWNLNN DTEVPTASVT IEGASALNRV RWSSGGKEVA VGDSEGRVWI YDTGELSVAH
TDDWARFART LMEIRANRAD GEEEGPMELA S
//
