ID A0A3P9BRP5_9CICH Unreviewed; 2833 AA.
AC A0A3P9BRP5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Jumonji domain containing 1C {ECO:0000313|Ensembl:ENSMZEP00005012613.1};
GN Name=JMJD1C {ECO:0000313|Ensembl:ENSMZEP00005012613.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005012613.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005012613.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR Ensembl; ENSMZET00005013057.1; ENSMZEP00005012613.1; ENSMZEG00005009463.1.
DR GeneTree; ENSGT00940000158210; -.
DR Proteomes; UP000265160; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0032454; F:histone H3K9 demethylase activity; IEA:InterPro.
DR Gene3D; 2.60.120.650; Cupin; 1.
DR InterPro; IPR045109; JHDM2-like.
DR InterPro; IPR003347; JmjC_dom.
DR PANTHER; PTHR12549; JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN; 1.
DR PANTHER; PTHR12549:SF6; JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 2C-RELATED; 1.
DR Pfam; PF02373; JmjC; 1.
DR SMART; SM00558; JmjC; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51184; JMJC; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265160}.
FT DOMAIN 2566..2790
FT /note="JmjC"
FT /evidence="ECO:0000259|PROSITE:PS51184"
FT REGION 263..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 546..567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 606..646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 691..820
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1065..1091
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1184..1218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1279..1309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1326..1433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1635..1677
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1696..1953
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2237..2278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2415..2448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..331
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..417
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 418..448
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..474
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..566
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 736..774
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1185..1200
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1279..1295
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1343..1358
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1390..1407
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1415..1433
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1696..1724
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1732..1781
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1799..1846
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1847..1950
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2237..2275
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2833 AA; 308872 MW; 3EB0E9B51E003345 CRC64;
MAVEARPELV GKRFLCVSGA EPPEIGDIGR WPWRSGVIRA VNHRDSDNAE LTVYVEFDDQ
EWDKREWVKV YEDFQLFLLE HQLVWAKRKE CAAAGGGGAG GLLQGSKAKH IQWPALTFKP
VVGERLLSSV AAVEFLLDRQ LDFLSDHSAY HPYQDEVDSQ SPVLRDNPQL HEEVKGWLKD
QKVQEIFMQG PYSLNGYRVR VYRQDSATQW FTGIITHHDL FSRNMVVMND QVLEPQNVDP
SMVQMTFLDD VVHSLLKGEN IGITSRRRSR SSQNNNAAHS HYTRAQANSP RPIMTSIGPN
SKASQGMLAS QQLSQSQQSQ QPASQLHHSP GGSGREQREQ RISRSSRRKG SDSSVPEEEK
DRREEPAGRE PKSKVKQSAN KRRKGDEDEK KAGPKKPKTD MTSDLSESSD SENPHNKRAA
HSSCSSSSST SSSSSSSSSS SSSEPNSENE LKTRSDVKPS AISKMEEDEK PLLQGPETND
SSSVIGRLSP WAELQATEDV KKSVVKETSK MLSKEDEELV AVTQITQSPR QQTPLMSDVV
QGGVLENSKN TVKASSRSQT PSLSHLHSAG VIDITDDAQA TVHRESSEAV SALLASEKAE
STALSPYLSL NPSPVSSPPV APSPSPSEGG RRTEMEPPVQ HQGILGGGVT ATKSVSSRLE
FASSEVIRPV TSIAENVLLV EKEKNVLPHH HLHQQQHHTL QSFHAGMKSP SLSEETRKHP
QQQPAPHKMN TVLPPDISKP QISSNPNPGS AHLDSLKQKS RPDSSQSPSY PNASQADLVK
AKAHAGLADI SKPKPNTSPE VSKHKMLRYS DTSPPPQSRL PVKIELAEPP RSGFKPVRLE
SGAVSTSSNT KSPLIIKKNE PFTVYRDPAL VRSDAENSAS ATVSSNHVAA YLHPHLHTLH
SPHSPCLTPA SHPHAASHLL APAHTSALPH PHLLPPTVLP AMAPPAASLH PRLDSPGGLG
HLALPHQQQY LQGQGHHSPS LLAQAHSGAA GLGLYPILWQ YPNGTPTSYP PGLNLGGPTA
KWVHPENPVT VNSEASLRRN AASPWLHKTA AADSLGMLSH VPVRPASADA HRPPVKIAHT
SPPLSKTSMD LHKEDVDKKG YVDPMRTMTL AQLKQEQTDR SRTPTGKDVH LHRLYLDPHS
KARLTSPQEA LQAADRACKY KEENRQILKE SIEVAPFTAK IQRSVDPAMD RDRERSRDSS
FCVRMPGLPS PSPKTSHALT HTMQSEKSNY YTTLSNSVVN EPPRLYPSKD VGPYYDKVSM
GAPGVVAGVG AAVQSPGALS MSSYHTSSKN SLSKPPPLIK HQPEGGEGLA GKITEQLSQQ
VTLVQPQHQL HAGVDRIDRR SPAISPPSST LSSSSSASNQ HHHHHHLQQQ QQLRAMPSLH
RAPVFHPPTQ HALERKEAAE RERAAHGGRL SPPTLTPIQP VTGSKTSAEQ QKPPTLLPEL
RDIKGHGTAA AITFVASATP GEMAAPSADG CKGRDLIEER GGVCSGDKGF SKNKPQSAMA
SVIVRSSIKY DSPVGAKKSG ALIHKELPQG RFYTSKFQDE CPREPAAGRV IQPNLNLEGY
KKTPVPGVSG PVGAGATNSV CRTAILVSSA FGSQSKTRSA TPEPVYSARC DFAALKPGTG
GRVLCHIRPE TEKELQEGFG SHASPGVSLN PASVAGAPRP SPSLTPTPSS ISGSSQPYAS
SFIHLKKHKA ALAAAKSRSN LSTPPSSVTA ENSSLTVDST EKTPISSSPP PPATSQASSV
SFDSSSNSSA SRSTTPGKSS PLLNGQSLGS ALPSSAQPNN YHKLKKAWLT RHSEEDRNTA
TTTSSSMKVE KSPSTTTTSN TAAMSEMIKP CTVNLSASTS NEVEMSKDIG SKGDRDRQPE
DKLAGAPGGG EERKVGSRRV NKRTYESGSE SGGDDSDTSE SKMEGRAKRQ PKPTYKKKQN
DMAKKKGDND REEDDVKPNG IFRSAREKTK LKLASSNGIP RSVLKDWRKV KKLKQTGESF
LQDDSCSEIG PNLQKCRECR VVRSKKGEEP AHSPVFCRFY YFRRLSYSKN GVIRMDGFST
PDQFDDEALS LWVPGPMEQS HLDQSTAKYI LSFIGDKFCQ MVATENTASS WIKKDAKLAW
KRAVRGVREM CDACEATLFN IHWVCQKCGF VVCLDCYKAK ERKSSKDKEL YGWLKCVKGQ
AHDHKHLMPT QIIPGSVLTD LVTSMHALRE KHNISSHCPC ASKQNLLTKL PATNGVSQVL
QNVLNHSNKL SLVKAEPGSL QTSDLGGVKS ETNGGGGGGT SPGNDGANAP ITPPESQSPL
HFLADLAERK SREEKKENKE SVVLGKSVKE DKEGDSLEVL QQCKTPSLGN STEQGSTLRD
LLTSTAGKLK LGSTDAGIAF APVYSAASQT GKGGRSMPNI LDDIIASVVE NKIPASRQNI
TTKLSAKQEP ITLSINNNAP AEEAKAEKKK SAPVTAAEAE DSSSQHPDIP HCWLNNRRLL
WLRDHRNQNN WKLFRECWKL GQPVLVSGIH KRLNASLWKA DSFNQEFADH QGDLLNCKDQ
VLSNSGIKEF WDGFEDITKR PKSKDGEPMV YRLMDWPSGE EFMALMPSRY DDLMKNLPLP
EYSDPEGNLN LASHLPSFFV RPDLGPRLCC AYGVAASQDQ DFGTAKLHVE VSDVVSVLVY
VGIAKGNGVL SKTGVLKRLE EEDLDEGVRK RLKDSSETPG ALWHIYLNRD MDKVRDFLHK
LSKEQGLDVS LDQDSIRKHA WYLSRKQRQR LLDEHGVQGW TVVQFLGDSV LIPAGAMHQV
QNLHSCVQVI NDFVSPEHVA NSFHLTQELR PNNEEVNYED KLQVKNILYH CVKEAASSLR
KSGSEKDDEE HNS
//
