ID A0A3P9BS21_9CICH Unreviewed; 394 AA.
AC A0A3P9BS21;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Transcriptional enhancer factor TEF-3 {ECO:0000313|Ensembl:ENSMZEP00005012753.1};
GN Name=TEAD4 {ECO:0000313|Ensembl:ENSMZEP00005012753.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005012753.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005012753.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005012753.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR002603}.
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DR AlphaFoldDB; A0A3P9BS21; -.
DR Ensembl; ENSMZET00005013197.1; ENSMZEP00005012753.1; ENSMZEG00005009355.1.
DR GeneTree; ENSGT00950000182956; -.
DR Proteomes; UP000265160; LG7.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0035329; P:hippo signaling; IEA:InterPro.
DR Gene3D; 2.70.50.80; -; 1.
DR Gene3D; 6.10.20.40; TEA/ATTS domain; 1.
DR InterPro; IPR000818; TEA/ATTS_dom.
DR InterPro; IPR038096; TEA/ATTS_sf.
DR InterPro; IPR016361; TEF_metazoa.
DR InterPro; IPR041086; YBD.
DR PANTHER; PTHR11834; TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED; 1.
DR PANTHER; PTHR11834:SF2; TRANSCRIPTIONAL ENHANCER FACTOR TEF-3; 1.
DR Pfam; PF01285; TEA; 1.
DR Pfam; PF17725; YBD; 1.
DR PIRSF; PIRSF002603; TEF; 2.
DR PRINTS; PR00065; TEADOMAIN.
DR SMART; SM00426; TEA; 1.
DR PROSITE; PS51088; TEA_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR002603};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR002603};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR002603};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR002603}.
FT DOMAIN 29..105
FT /note="TEA"
FT /evidence="ECO:0000259|PROSITE:PS51088"
FT DNA_BIND 29..105
FT /note="TEA"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00505"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 394 AA; 44766 MW; 7786F9BEDF3ED214 CRC64;
SDPLPLWVPA PSPRGGSEEL GDGLDKPLEN DAEGVWSPDI EQSFQEALAI YPPCGRRKII
LSDEGKMYGR NELIARYIKL RTGKTRTRKQ VSSLQIPFVA VGVDRRLSCQ QSAETTQLII
KSLHNAHTNR SNFSALSTFT QVTVKRHVHM VAAFSSAVYD NTQGLSMSPG APPWQGRSIA
SSKLRMLEFS AFLEQPQDPE TFNKHLFVHI GQSNPSYSDP YLESVDIRQI YDKFPEKKGG
LKELFDKGPP NAFFLVKFWA DLSVNLQDDS SFFYGVSSQY ESSENMIITS STKVCSFGKQ
VVEKVETEYA RFENGRYVFR IHRSPLCEYM INFIHKLKHL PEKYMMNSVL ENFTILQVVT
NRDTLETLLC IAYVFEVSTS EHGAQHHIYR LVKD
//
