ID A0A3P9BWQ5_9CICH Unreviewed; 274 AA.
AC A0A3P9BWQ5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Elongator complex protein 6 {ECO:0000256|ARBA:ARBA00020263};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005014420.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005014420.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005014420.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA
CC biosynthesis. {ECO:0000256|ARBA:ARBA00005043}.
CC -!- SIMILARITY: Belongs to the ELP6 family.
CC {ECO:0000256|ARBA:ARBA00008837}.
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DR AlphaFoldDB; A0A3P9BWQ5; -.
DR STRING; 106582.ENSMZEP00005014420; -.
DR Ensembl; ENSMZET00005014900.1; ENSMZEP00005014420.1; ENSMZEG00005010854.1.
DR GeneTree; ENSGT00390000011734; -.
DR OrthoDB; 5475160at2759; -.
DR UniPathway; UPA00988; -.
DR Proteomes; UP000265160; LG11.
DR GO; GO:0033588; C:elongator holoenzyme complex; IEA:InterPro.
DR GO; GO:0002098; P:tRNA wobble uridine modification; IEA:InterPro.
DR CDD; cd19495; Elp6; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR018627; ELP6.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR16184; ELONGATOR COMPLEX PROTEIN 6; 1.
DR PANTHER; PTHR16184:SF6; ELONGATOR COMPLEX PROTEIN 6; 1.
DR Pfam; PF09807; ELP6; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000265160}.
SQ SEQUENCE 274 AA; 30224 MW; E20D0A13F076626D CRC64;
MFTELNSILN ATPDSFTQGE FILVSDRQSD ASFLIHHFLS FYLRARCKVC FLGLVQSFSH
YSAISQRLGV SLTQAREKGQ LIFLEGLKES LSILIPQETT TGSQAMDFLR DPTVGLQRLY
EFVRSSVSSD GGGEEGVEEW GPPVLLVDDI SVLLSLGVSA GAALDFSHYC RATVCSQLQG
NIVMLVRCHG EEAEDDGSDE GSEWLLKGLT HQCSLTLHVQ GLPTGYCRDI HGQVEVCWRR
RRGDGQHTQK KLFQYKVHDK GASFFAPGTS SAVL
//
