GenomeNet

Database: UniProt
Entry: A0A3P9BXZ3_9CICH
LinkDB: A0A3P9BXZ3_9CICH
Original site: A0A3P9BXZ3_9CICH 
ID   A0A3P9BXZ3_9CICH        Unreviewed;      2847 AA.
AC   A0A3P9BXZ3;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   10-FEB-2021, entry version 12.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMZEP00005014516};
OS   Maylandia zebra (zebra mbuna).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX   NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005014516, ECO:0000313|Proteomes:UP000265160};
RN   [1] {ECO:0000313|Ensembl:ENSMZEP00005014516, ECO:0000313|Proteomes:UP000265160}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=25186727; DOI=10.1038/nature13726;
RA   Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA   Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA   Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA   Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA   Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA   Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA   Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA   Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA   Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA   Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA   Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA   Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA   Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA   Di Palma F.;
RT   "The genomic substrate for adaptive radiation in African cichlid fish.";
RL   Nature 513:375-381(2014).
RN   [2] {ECO:0000313|Ensembl:ENSMZEP00005014516}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (DEC-2018) to UniProtKB.
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DR   RefSeq; XP_004539548.1; XM_004539491.1.
DR   Ensembl; ENSMZET00005014999; ENSMZEP00005014516; ENSMZEG00005010919.
DR   GeneID; 101473863; -.
DR   CTD; 1063; -.
DR   GeneTree; ENSGT00730000111187; -.
DR   Proteomes; UP000265160; LG1.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 2.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265160}.
FT   DOMAIN          1..306
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1811..1953
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2049..2191
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2743..2787
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          120..141
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          221..280
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          447..518
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          550..588
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1064..1099
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1639..1686
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2244..2274
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2299..2338
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2356..2432
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2656..2847
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          20..82
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          162..196
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          645..672
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          684..714
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          719..760
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          779..814
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          818..961
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          979..1041
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1130..1220
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1231..1265
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1270..1444
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1466..1529
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1689..1793
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1815..1849
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1892..1912
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1920..1968
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2540..2578
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2582..2630
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        258..280
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        472..488
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        556..588
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2253..2274
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2299..2313
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2356..2377
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2385..2432
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2670..2690
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2691..2706
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2742..2756
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2810..2824
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2847 AA;  326531 MW;  D9DEE848D5B0835E CRC64;
     MSWAVEEWKD GLPGKALQKI QEMEVQLDKL KKEKTQKQFQ LDSLEAALQK QKQKVDSERT
     ETSALKRENQ SLLESCDSLE KARQKVVHDL GVKEQQVSYL EGQLNSCRKT IERLEQELKK
     HKNELDRSQP AGSSSLSSSS CELQTYATPQ KSFQTPASIP AYRQHDNRLE ELQEKYNQEV
     EERKRLESEL KVLQVKLLNQ SSVSVSHKDI AARQAGSSIF PWQQQDSAHR RQSQDIMETP
     LKRRGTSLWD AHEETPIKPS QRMSSSRAAP SPSGSSQQME QLKTLNQELR GHVSELERNL
     ANQEKEIRNQ ASKLQDLQTQ LNQARKDLSE RDRDLTKAKH ELSQATDRHQ QVESKCSSVE
     QKLKQVTEEM SCQRHNAESC RRALEQKLKD QERDSQKELA QLQSSHHALD QQLNQTRTKL
     TQEIQQAKKD HNILQADMEK MCFQKKQMEK EMEEQKQKLL RSEQSLQACQ TKEQDLRKKM
     EELQKEKNSM TVQLDQSNRR LSQLEEEKKS SNQSLKRTQG LLDDLKAKSE GQAEELKKLQ
     CKLEQQAQTS AREQENLKKT LSDAETRNDR SQNELQKQKQ ESERLSNRVT VLEKESQELK
     SNLSASQNEC KELKREHQAL LDWKNEKESL INETEAVQKE FADKITSLES SLGSLNEAND
     ELQKKLTCVE GEKASLSAHI DSLKGELLNK CTDLEEKAHQ YKELQSQFSE AGQKHAKDLE
     NIGVQVAQLE AQVKDLELRL QKEITRAELA ERMNTDLQDE HKATCDLVRS KEQLVELGRA
     EISQLRESLA QTIAQQEEQN ARLAEEKADL LKQCEERVSA KAEETEHIKL QLEEAQQELL
     LTKNQISSLE QFLKVQEQLG AELQKQIKTM TEQEEEQIRM YNKKSEELKQ LEMDLSDQRK
     QTEKKEKQLR EAEVQISSVE KQKAELENEI QDLKKESKII QHSQTEKISS LLEQISSLEE
     KVDVNKDAAE KLPVLKNELD VATQSNTDLK KSLQALEENH SSAIEIKSNL ESTLAEKMNL
     ISALENEVKD LTEKMGKESE RHALEIENFL NKKKSLDEQL EATKKSVSAA KAESSSRREE
     IRTMKATLSA ASRGLEERDS TIKDLKEKLN KAEAEQTKTS ELLKEKVVAM NKIKVQLEML
     QMDLEDNETA MTSFDSQVEQ LKGTIESLEA MLAQSQTQMS EMEAMLDEGR AQVSVLEARL
     DEVQSQNSLL ESKYVTAKEE LFERTCEITR MEEEAIRRHE LEESVATLEA KLSQMTQDNE
     KLETTLGETI QDKESSLNQL LQEKNNLETS LKQLMNDKEQ VEGEMVHVNA EKKLLEVTVD
     ALSEENKQLQ SNIEQVTEEK QQTEAKINEI TARKHEAESA LSQLTEAKAQ LDDILKKTNE
     ENVQLADELH ALTSEKNDLV TKLNQVVEEK VQLELSYNQL SEENIKLQSN VNQITEEKLQ
     LQELIKGHGD EVASLREESE CIQHSLLTSE QERQRLKEQL ELMEERTEAT NKEQSERFTA
     EQAELHQKLA GLQKELTVFK QQYESLLEQV GQQHSLIQQL SEFKSPADRN NMEEAETDVY
     PAEAAAESQV EPAVNSSLCT SSESLPVEEE LMVSEPTEFA DAFSEVKLVF KVDATKQEVT
     QEQSEDDGEA FVADVEETKT NEEEQLLPEQ VSEESSNSRD VLVDESVIHD VSPQPSSFSE
     KRDTKSFESS LVNDELERYK EMIRKQEKEL ETLRSEFDLL SSDLELRKEL TSELEVQVQN
     LEQKVHAAEE EAHSASCQLK IALDSKKNLS HELTQLSEEK ETLTLQLQTT KCQLTDVMEM
     LEGLEMAKGG WDEKFLQQES ELKRVRSEKA NLEQHILGME SELETMQAEG ARLKGEMETQ
     RRTFSGMEQK IETLITETTQ LRSELVSCTE ERDELSQSLS HWREKVHSLE KNNCDTRNLI
     SILEDDIRAG RKEYEALQSN TDKLRTERQQ LVEQVKELER TISQHCGERE ELIGHLNQIK
     EDHSSSSQNT ESMAGKIKAL EGEVFRLSQS LESSLLEKGE IASRLNSTQD EVQQMRTGIE
     KLQVRIESDE RKKKKMGELL KAAQRKSDSL QDRIDSLERE KEDVEQSLEE AVLQAEMAKA
     ELEEERRMVE EEKKELSAKI SELSTTLESL KSEKEHMERQ LEIKNREIKE LKAAKEELER
     GLEKAEAERK EEEERQKCRL EELEKEMKGE AERQIRVLDD LQAQLEASRQ REISLEQKGT
     EGEAEKERMQ ALLVQLEEEK KHLLSSLQES QTEGEKLRSH GEEWETERNS LRTQTEALEE
     EIQELKTLIK TTEDKMEVLE KEKEEDRDQK QALERSVSSV MAEKEQIEGE NGRLVQEKEE
     LRTALLSLEQ ERDKLRSSLL SVEDEKERLD QGRSALASER EELQSSLSLL DKEKHDLQQK
     LSFLNQEKER EEEEKQKIEA EKQELKSSVS LMEEEKKNLS SALLSLEQEK EKLAEEHEHL
     KTAVTSMEKE LETHKVSISQ LSEQVSELTS RAARLTKDKN SALSKMSLWM KTCKQLEQEK
     EMMLNGSGAG KSSEEGPTEL TQLRKDAEKL KEEVENLKSA LEQKMTEAEE RLMASQEKDQ
     EVNKLSAALD GKRKELEEKV KELEEMKTEL EEVNKLLEEK SKEADESMEK YCSLMLEVHK
     LEKTNEALKT RLELIGASQN ANDSHSSSTE GRQRSGRKSS TRHQEIKIDD NTENIAPSTT
     QRSPPGSGKR GHCEISTRDS AQEALHNVTK RIKANATTTP KSRPEQEDEE FRPEGLPELV
     QRGFADIPLG EASPFIIRRT TVRRCSPRLA AKQTASDGKG LGPIPLQSPS AAMATDTANR
     KCSPSSRKTP EKQLREQTQQ GDNCHVQ
//
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