ID A0A3P9BXZ3_9CICH Unreviewed; 2847 AA.
AC A0A3P9BXZ3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 10-FEB-2021, entry version 12.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMZEP00005014516};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005014516, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005014516, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005014516}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (DEC-2018) to UniProtKB.
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DR RefSeq; XP_004539548.1; XM_004539491.1.
DR Ensembl; ENSMZET00005014999; ENSMZEP00005014516; ENSMZEG00005010919.
DR GeneID; 101473863; -.
DR CTD; 1063; -.
DR GeneTree; ENSGT00730000111187; -.
DR Proteomes; UP000265160; LG1.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 2.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 2.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160}.
FT DOMAIN 1..306
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 1811..1953
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2049..2191
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2743..2787
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 120..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 221..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 447..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 550..588
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1064..1099
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1639..1686
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2244..2274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2299..2338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2356..2432
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2656..2847
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 20..82
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 162..196
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 645..672
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 684..714
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 719..760
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 779..814
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 818..961
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 979..1041
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1130..1220
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1231..1265
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1270..1444
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1466..1529
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1689..1793
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1815..1849
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1892..1912
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1920..1968
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2540..2578
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2582..2630
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 258..280
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 472..488
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..588
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2253..2274
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2299..2313
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2356..2377
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2385..2432
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2670..2690
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2691..2706
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2742..2756
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2810..2824
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2847 AA; 326531 MW; D9DEE848D5B0835E CRC64;
MSWAVEEWKD GLPGKALQKI QEMEVQLDKL KKEKTQKQFQ LDSLEAALQK QKQKVDSERT
ETSALKRENQ SLLESCDSLE KARQKVVHDL GVKEQQVSYL EGQLNSCRKT IERLEQELKK
HKNELDRSQP AGSSSLSSSS CELQTYATPQ KSFQTPASIP AYRQHDNRLE ELQEKYNQEV
EERKRLESEL KVLQVKLLNQ SSVSVSHKDI AARQAGSSIF PWQQQDSAHR RQSQDIMETP
LKRRGTSLWD AHEETPIKPS QRMSSSRAAP SPSGSSQQME QLKTLNQELR GHVSELERNL
ANQEKEIRNQ ASKLQDLQTQ LNQARKDLSE RDRDLTKAKH ELSQATDRHQ QVESKCSSVE
QKLKQVTEEM SCQRHNAESC RRALEQKLKD QERDSQKELA QLQSSHHALD QQLNQTRTKL
TQEIQQAKKD HNILQADMEK MCFQKKQMEK EMEEQKQKLL RSEQSLQACQ TKEQDLRKKM
EELQKEKNSM TVQLDQSNRR LSQLEEEKKS SNQSLKRTQG LLDDLKAKSE GQAEELKKLQ
CKLEQQAQTS AREQENLKKT LSDAETRNDR SQNELQKQKQ ESERLSNRVT VLEKESQELK
SNLSASQNEC KELKREHQAL LDWKNEKESL INETEAVQKE FADKITSLES SLGSLNEAND
ELQKKLTCVE GEKASLSAHI DSLKGELLNK CTDLEEKAHQ YKELQSQFSE AGQKHAKDLE
NIGVQVAQLE AQVKDLELRL QKEITRAELA ERMNTDLQDE HKATCDLVRS KEQLVELGRA
EISQLRESLA QTIAQQEEQN ARLAEEKADL LKQCEERVSA KAEETEHIKL QLEEAQQELL
LTKNQISSLE QFLKVQEQLG AELQKQIKTM TEQEEEQIRM YNKKSEELKQ LEMDLSDQRK
QTEKKEKQLR EAEVQISSVE KQKAELENEI QDLKKESKII QHSQTEKISS LLEQISSLEE
KVDVNKDAAE KLPVLKNELD VATQSNTDLK KSLQALEENH SSAIEIKSNL ESTLAEKMNL
ISALENEVKD LTEKMGKESE RHALEIENFL NKKKSLDEQL EATKKSVSAA KAESSSRREE
IRTMKATLSA ASRGLEERDS TIKDLKEKLN KAEAEQTKTS ELLKEKVVAM NKIKVQLEML
QMDLEDNETA MTSFDSQVEQ LKGTIESLEA MLAQSQTQMS EMEAMLDEGR AQVSVLEARL
DEVQSQNSLL ESKYVTAKEE LFERTCEITR MEEEAIRRHE LEESVATLEA KLSQMTQDNE
KLETTLGETI QDKESSLNQL LQEKNNLETS LKQLMNDKEQ VEGEMVHVNA EKKLLEVTVD
ALSEENKQLQ SNIEQVTEEK QQTEAKINEI TARKHEAESA LSQLTEAKAQ LDDILKKTNE
ENVQLADELH ALTSEKNDLV TKLNQVVEEK VQLELSYNQL SEENIKLQSN VNQITEEKLQ
LQELIKGHGD EVASLREESE CIQHSLLTSE QERQRLKEQL ELMEERTEAT NKEQSERFTA
EQAELHQKLA GLQKELTVFK QQYESLLEQV GQQHSLIQQL SEFKSPADRN NMEEAETDVY
PAEAAAESQV EPAVNSSLCT SSESLPVEEE LMVSEPTEFA DAFSEVKLVF KVDATKQEVT
QEQSEDDGEA FVADVEETKT NEEEQLLPEQ VSEESSNSRD VLVDESVIHD VSPQPSSFSE
KRDTKSFESS LVNDELERYK EMIRKQEKEL ETLRSEFDLL SSDLELRKEL TSELEVQVQN
LEQKVHAAEE EAHSASCQLK IALDSKKNLS HELTQLSEEK ETLTLQLQTT KCQLTDVMEM
LEGLEMAKGG WDEKFLQQES ELKRVRSEKA NLEQHILGME SELETMQAEG ARLKGEMETQ
RRTFSGMEQK IETLITETTQ LRSELVSCTE ERDELSQSLS HWREKVHSLE KNNCDTRNLI
SILEDDIRAG RKEYEALQSN TDKLRTERQQ LVEQVKELER TISQHCGERE ELIGHLNQIK
EDHSSSSQNT ESMAGKIKAL EGEVFRLSQS LESSLLEKGE IASRLNSTQD EVQQMRTGIE
KLQVRIESDE RKKKKMGELL KAAQRKSDSL QDRIDSLERE KEDVEQSLEE AVLQAEMAKA
ELEEERRMVE EEKKELSAKI SELSTTLESL KSEKEHMERQ LEIKNREIKE LKAAKEELER
GLEKAEAERK EEEERQKCRL EELEKEMKGE AERQIRVLDD LQAQLEASRQ REISLEQKGT
EGEAEKERMQ ALLVQLEEEK KHLLSSLQES QTEGEKLRSH GEEWETERNS LRTQTEALEE
EIQELKTLIK TTEDKMEVLE KEKEEDRDQK QALERSVSSV MAEKEQIEGE NGRLVQEKEE
LRTALLSLEQ ERDKLRSSLL SVEDEKERLD QGRSALASER EELQSSLSLL DKEKHDLQQK
LSFLNQEKER EEEEKQKIEA EKQELKSSVS LMEEEKKNLS SALLSLEQEK EKLAEEHEHL
KTAVTSMEKE LETHKVSISQ LSEQVSELTS RAARLTKDKN SALSKMSLWM KTCKQLEQEK
EMMLNGSGAG KSSEEGPTEL TQLRKDAEKL KEEVENLKSA LEQKMTEAEE RLMASQEKDQ
EVNKLSAALD GKRKELEEKV KELEEMKTEL EEVNKLLEEK SKEADESMEK YCSLMLEVHK
LEKTNEALKT RLELIGASQN ANDSHSSSTE GRQRSGRKSS TRHQEIKIDD NTENIAPSTT
QRSPPGSGKR GHCEISTRDS AQEALHNVTK RIKANATTTP KSRPEQEDEE FRPEGLPELV
QRGFADIPLG EASPFIIRRT TVRRCSPRLA AKQTASDGKG LGPIPLQSPS AAMATDTANR
KCSPSSRKTP EKQLREQTQQ GDNCHVQ
//
