ID A0A3P9C231_9CICH Unreviewed; 813 AA.
AC A0A3P9C231;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Liprin-beta-2 {ECO:0000313|Ensembl:ENSMZEP00005016303.1};
GN Name=PPFIBP2 {ECO:0000313|Ensembl:ENSMZEP00005016303.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005016303.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005016303.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005016303.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the liprin family. Liprin-beta subfamily.
CC {ECO:0000256|ARBA:ARBA00007547}.
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DR AlphaFoldDB; A0A3P9C231; -.
DR STRING; 106582.ENSMZEP00005016303; -.
DR Ensembl; ENSMZET00005016823.1; ENSMZEP00005016303.1; ENSMZEG00005012230.1.
DR GeneTree; ENSGT01050000244951; -.
DR Proteomes; UP000265160; LG1.
DR CDD; cd09563; SAM_liprin-beta1_2_repeat1; 1.
DR CDD; cd09566; SAM_liprin-beta1_2_repeat2; 1.
DR CDD; cd09569; SAM_liprin-beta1_2_repeat3; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 3.
DR InterPro; IPR029515; Liprin.
DR InterPro; IPR037617; Liprin-beta_SAM_rpt_1.
DR InterPro; IPR037618; Liprin-beta_SAM_rpt_2.
DR InterPro; IPR037619; Liprin-beta_SAM_rpt_3.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR12587; LAR INTERACTING PROTEIN LIP -RELATED PROTEIN; 1.
DR PANTHER; PTHR12587:SF18; LIPRIN-BETA-2; 1.
DR Pfam; PF00536; SAM_1; 2.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00454; SAM; 3.
DR SUPFAM; SSF47769; SAM/Pointed domain; 3.
DR PROSITE; PS50105; SAM_DOMAIN; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 486..550
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 563..621
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 112..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 255..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 438..474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 778..813
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 145..200
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 113..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 255..386
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 387..403
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 813 AA; 90351 MW; ABB2E4830C43ED6D CRC64;
MNKELLHRAS LENQKLSLMG EVSYLKLKLA DMEGKQGHGG ERQHKAETVV NFISELQEQI
YQFQKEINSK IQEKKALEIP NDSRLPVECP AESSESQDSN LGVPCDKTSG IVNKLEDTPN
GADGNTTTLE EGSSDAEQKY YCGGESGLLK ELRILKDKVE HLEDQKLQYE KKLKATKAEI
SSLQQLLHSK NAEIESLHSQ LLARPSLTTE STERDQELQK LRSGMKSLAA ANDEKDRRIE
ELTLLLNQCR QFREVSSKAR QAPSAVRTLS NGRSLSSSSE EEEQGLMKNG DTSSAKSEDV
KSEASTNSSA SQQTSISSVQ KDSDSRSEVQ TLSSSMNDIT NGSAQKTGPS EMRSHTLPVN
SSLSEQNGIG DSSSEIQSQR SPAGSEDGDS SQRKPEKGDD STSSDTSPVH SGQRAVGSPE
YMKNNRSFKR LWGKLRRTQS GGLPATDPDS GQFRRGGLRA TAGPRLTRTP ESFDSARDMN
IPFSQWTKEQ VCGWLEDYGL GQYVSLSRQW VENGQTLLSA TPQDFEKEMG LKNPLHRKKL
QLALRAFTTK AIEKSSELDH IWVTRWLDDI GLPQYKDQFH EARIDGRMIQ YLTVNDLLTL
KVTSQLHHLS IKCAIHVLHA NKFNPNCLRR RPVEEKHPPP SEVVQWSNHC VMEWLRAVDL
AEYAPNLRGS GVHGGLIILE PRFSSETLAL LLNIPPQKTL LRRHLATAFS ALVGLQAMQE
KREYGNATGH VPLTTTAKVK PKKLGFTQFS HLRKRKPDES ADYICPIDSG ALTVNGVSRL
PSSAQRGLSP RLDRQAEREE QVGIKAQTNG PKQ
//
