ID A0A3P9C5N2_9CICH Unreviewed; 467 AA.
AC A0A3P9C5N2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Inner centromere protein A {ECO:0000313|Ensembl:ENSMZEP00005017359.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005017359.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005017359.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005017359.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_004543098.1; XM_004543041.3.
DR AlphaFoldDB; A0A3P9C5N2; -.
DR Ensembl; ENSMZET00005017908.1; ENSMZEP00005017359.1; ENSMZEG00005013047.1.
DR GeneID; 101482374; -.
DR KEGG; mze:101482374; -.
DR GeneTree; ENSGT00940000174693; -.
DR OrthoDB; 2884126at2759; -.
DR Proteomes; UP000265160; LG1.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR003656; Znf_BED.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR PANTHER; PTHR34396:SF28; BED-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR34396; OS03G0264950 PROTEIN-RELATED; 1.
DR Pfam; PF02892; zf-BED; 3.
DR SMART; SM00614; ZnF_BED; 3.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR PROSITE; PS50808; ZF_BED; 3.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00027}.
FT DOMAIN 4..56
FT /note="BED-type"
FT /evidence="ECO:0000259|PROSITE:PS50808"
FT DOMAIN 134..185
FT /note="BED-type"
FT /evidence="ECO:0000259|PROSITE:PS50808"
FT DOMAIN 275..327
FT /note="BED-type"
FT /evidence="ECO:0000259|PROSITE:PS50808"
FT REGION 48..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 189..211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 251..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 406..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 336..356
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 467 AA; 52801 MW; 1896601A2F133158 CRC64;
MVRARSSVVW SFFENNDSRS VRCLLCARHL LKKGCGSTTA MLRHLRVKHP TELSTRSNGP
GSKPGPGEDQ HHRAEGEQFC SVEVALEDDE GGTITAVHTT GISSSLNDLL PQEGPSEIIT
QMETSDERPV KRSRHRSVIW KHFDCLDNLN AVRCRICMKK LVESGGVSNL RRHLSSKHPK
VYSELLSTQQ YPPTPLNSSQ DSNTNPESDE ALWGTEQSDA QVEVLSKDRD SETVTLVNET
DNSVAINGIL DASHGNPAEP QTHTEGSDDL PAGRPLRSTI WRHFERLDSL NAARCRICTK
KLKCGKNSSS NLHRHMSKRH PNLLLEQVSN GLRLPALNSS PVSHANNKTS EQRQAPGALK
MSEGEKRTLK RERELIEALR RTQKEEARTL EHQRELLEKL RAASAREAAA EREQIESLRK
AQQEEANDLS RQREELQKEK EELQKKWEEL QQEREELLLF SREQQVS
//
