ID A0A3P9C6M8_9CICH Unreviewed; 629 AA.
AC A0A3P9C6M8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Heterogeneous nuclear ribonucleoprotein Q {ECO:0000313|Ensembl:ENSMZEP00005017762.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005017762.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005017762.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005017762.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3P9C6M8; -.
DR STRING; 106582.ENSMZEP00005017762; -.
DR Ensembl; ENSMZET00005018337.1; ENSMZEP00005017762.1; ENSMZEG00005013344.1.
DR GeneTree; ENSGT00940000153511; -.
DR Proteomes; UP000265160; LG15.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd21066; NURR_hnRNPQ; 1.
DR CDD; cd12495; RRM3_hnRNPQ; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR041337; hnRNP_Q_AcD.
DR InterPro; IPR006535; HnRNP_R/Q_splicing_fac.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01648; hnRNP-R-Q; 1.
DR PANTHER; PTHR21245; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; 1.
DR PANTHER; PTHR21245:SF11; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Q; 1.
DR Pfam; PF18360; hnRNP_Q_AcD; 1.
DR Pfam; PF00076; RRM_1; 3.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR PROSITE; PS50102; RRM; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265160};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 162..241
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 243..325
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 338..408
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 138..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 427..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 491..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..629
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 629 AA; 70156 MW; 155BCFD6A534AF1E CRC64;
MATDHVNGNG TEEPMDTTAE VTHSEHFQAL LEAGLPQNVA EKLDELYVAG LVAHGDLDER
AIEALKEFNE DGALQVLVQF KESDLSHVQN KSAFLCGVMK TYRQREKQGT KVSDSIKGPD
EAKIKELLER TSYTLDVTTG QRKYGGPPPE SVYSGSQPPV GTEIFVGKIP RDLYEDELVP
LFEKAGPIWD LRLMMDPLSS LNRGYAFITF CSKEGAQEAV KLCNNHEIRP GKHIGVCISV
ANNRLFVGSI PKSKTKEQIV EEFSKVTEGL SDVILYHQPD DKKKNRGFCF LEYEDHKTAA
QARRRLMSGK VKVWGNLVTV EWADPIEDPD PEVMAKVKVL FVRNLANGVT EELLETSFSE
FGKLERVKKL KDYAFIHFEE RDGAVKALEE MNGKELEGEP IEIVFAKPPD QKRKERKAQR
QAAKTQMYDD YYYYPPPPHM PPPSRNRGRG GNRGGYAYPP DYYGYEDYYD YYGYDYHNYR
GGYDDPYYGY DDFQAPSRGR GGSRGARGGS SPARGRGGSG APRGRANFSQ RGGPGPGRGG
RGARGGVQLR GRGGVRGARG GRGGNVGGKR KADGYNQPDS KRRQTNNQNW GSQPIAQQPL
QGGDHSGNYS GYKSDNQEFY QDSFGQQWK
//
