ID A0A3P9C880_9CICH Unreviewed; 735 AA.
AC A0A3P9C880;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Leucine-rich repeat flightless-interacting protein 2 {ECO:0000313|Ensembl:ENSMZEP00005018274.1};
GN Name=LRRFIP1 {ECO:0000313|Ensembl:ENSMZEP00005018274.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005018274.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005018274.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005018274.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the LRRFIP family.
CC {ECO:0000256|ARBA:ARBA00008275}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3P9C880; -.
DR Ensembl; ENSMZET00005018865.1; ENSMZEP00005018274.1; ENSMZEG00005013703.1.
DR GeneTree; ENSGT00530000063564; -.
DR Proteomes; UP000265160; LG16.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.20.5.4090; -; 1.
DR InterPro; IPR019139; LRRFIP1/2.
DR PANTHER; PTHR19212; LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN; 1.
DR PANTHER; PTHR19212:SF5; LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 1; 1.
DR Pfam; PF09738; LRRFIP; 3.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160}.
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 90..195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 256..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 555..583
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 608..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 712..735
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 356..481
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 90..115
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..150
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..195
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..580
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 610..626
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 712..727
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 735 AA; 83027 MW; A462780AEEAE8B0B CRC64;
MGTQGTGRKR STKKDKTTAE DDALNLIARE AEARLAAKRA ARAEAREIRM KELERQQKEI
FQVQKKYYGL NTKLDDRVDN KWGDIEQWME DSERYSRPSR IHMLSDDDER MSVGSRGSAR
SDLDAVGAYG GGGSSSHKKS KKKKKHKHKD RDRNGCDDEY SVISDRSSRL SDESRVSRSR
LDLTSSRLSD DSRLSRVSRS DLQLASYASS DLYSLNGLSS SRNPGSAFNG YQSSLYEDSL
CSGSRRVISA GSHPVEYTSY RSSGSRTSSR AGSARTSPVG NCSSVASFLR SSSSGLPRDL
DDVTIPDFPD VEDRDYLEKG SRAASALTAA TLTSLGGSSS RRGSGETALT VDAESSIREI
KEIHELKDQI QEVEAKYTQN LKEVKDALAE VEEKYRKAMV SNAQLDNEKN NLMYQVDTLK
DSLMELEELL TESRREHEEK VKEYEREKYA HSVLQFQFNE MKETLKQSEE LLNEIRQLRL
KQEGFVREIT DLQETVEWKD KKIGALERQK EYTDAIRIER DELREEAVKL KDILKKHGIV
LGPDLSINGD VDVAEADESS SVDPASQPAQ ESQTTPAEGN SMLEIRLRKL VDEREKMIEQ
VKKLKAQLEQ KTQKNGTDTS PDAEIIENGN DPNIMELQRD SNRQISELKF KLVKAEQEAT
ALEQNVTRLE GQVTRYKSAA ENAEKIEDDL KAEKRKLQRE LRSALDKIEE LESNNSHLSK
RLEKMKSSRG MAQTP
//
