ID A0A3P9CCF2_9CICH Unreviewed; 632 AA.
AC A0A3P9CCF2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=DUF4371 domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005019980.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005019980.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005019980.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P9CCF2; -.
DR STRING; 106582.ENSMZEP00005019980; -.
DR Ensembl; ENSMZET00005020626.1; ENSMZEP00005019980.1; ENSMZEG00005015003.1.
DR GeneTree; ENSGT00940000164001; -.
DR Proteomes; UP000265160; LG15.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR InterPro; IPR025398; DUF4371.
DR InterPro; IPR008906; HATC_C_dom.
DR InterPro; IPR012337; RNaseH-like_sf.
DR PANTHER; PTHR45749; -; 1.
DR PANTHER; PTHR45749:SF29; DIMER_TNP_HAT DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF05699; Dimer_Tnp_hAT; 1.
DR Pfam; PF14291; DUF4371; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265160}.
FT DOMAIN 56..225
FT /note="DUF4371"
FT /evidence="ECO:0000259|Pfam:PF14291"
FT DOMAIN 544..602
FT /note="HAT C-terminal dimerisation"
FT /evidence="ECO:0000259|Pfam:PF05699"
SQ SEQUENCE 632 AA; 70971 MW; 872F220FBB5E60D3 CRC64;
MAIVYKAFQL FGNRIHEMAQ THKDSVVTWK SYQGTSKQGN VAQMIATANV SEIVERREYL
RRIVAVTSML GRQGLPFRGH DEGEDSPNRG NFLACMELLK EFDPFLQKHN PPSNAQYISP
TSQNDMIDCC AQEVTSVIVS EMTKSKVYSI MVDEARDKKA EQLAVCVRYV SEGAVKERFL
ALAEIKSFDA QSIVNEIQQQ IQNYGLAELK CVAQTYDGAA VMSGSTGGVQ AHFRRLHPEA
IYVHCYAHQL NLVLCNTCKA VPEAVELFSL LECVYSFFST SLVNHHKFME TQAKLGLTKT
ELVQLSNTRW ACQLRSISAV LETLPAILEC LSAIGSPIAV GLRAKLYKFS AVYALLMFQS
ILSVTEGLHK FLQKETLDLA EAFICKQAVC DTLKGKHSDA FATELYEKTK ALCNTHSIPE
PGAKTRHKQR KMEDFVLEAT VGSRTELNNS DTLKRELLFP CVDRMVGELD QRFCSVDAGL
LKGVQACSPK SENFLSEPHL NELAKHYRLD LKKEEVLVAR NFLTRKTEAG CPPKNMLSVY
NLLDSDMFPS LKATIQVALT VPVSSCSCER SFSALRRLHS WLRQTMGQKR LHSLAVMSIE
KDTLQHLSHN RVIDRFATLK NRRHSLMLPP TK
//
