ID A0A3P9CHV5_9CICH Unreviewed; 773 AA.
AC A0A3P9CHV5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Sarcolemma associated protein {ECO:0000313|Ensembl:ENSMZEP00005021865.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005021865.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005021865.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005021865.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P9CHV5; -.
DR Ensembl; ENSMZET00005022581.1; ENSMZEP00005021865.1; ENSMZEG00005016312.1.
DR GeneTree; ENSGT00940000157660; -.
DR Proteomes; UP000265160; LG5.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd21911; CC1_SLMAP; 1.
DR CDD; cd22679; FHA_SLMAP; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR15715; CENTROSOMAL PROTEIN OF 170 KDA; 1.
DR PANTHER; PTHR15715:SF26; COILED-COIL DOMAIN-CONTAINING PROTEIN 136; 1.
DR Pfam; PF00498; FHA; 1.
DR SMART; SM00240; FHA; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 743..764
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..85
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT REGION 377..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 172..199
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 467..512
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 556..590
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 629..702
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 388..410
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 773 AA; 88491 MW; 3D4DC5DF1062CD0B CRC64;
MPSALAIFAC RPNSHPFQER HVYLDEPVKI GRSVARCRPA QNNATFDCKV LSRNHALVWF
DHKTGKFYLQ DTKSSNGTFI NSQRLSRGSE ESPPCEVLSG DIIQFGVDVT ENTRKVTHGC
IVSTIKLFLP DGMEARRRSD VIQPPLPLPI DKVAANTPSM YSQELFQLSQ YLQEALHREQ
MLEQKLATLQ RLLATTQEAS ESSWQALIDE DRLLSRLEVM GSQLQAYSKS QTEEGIRKEL
LALQEDKHNY ETTAKESLRR VLQEKIEVVR KLSEVERTLS NTEDECTHLK EMSERSQEEL
RELANKYNAA VNEIKELTDK IKAAEGRQEE LTQRGATEKR ELELRIEEME EKEQVLQARI
EALQADNDFT NERLAALQGT NTRNQMDAKE SDMSDTLSPS KDRSSDDTSD GNMNDQELNE
PQNRVALLKD ELHRAGLEPG DTEQVIHHLH RELLEAQELA NTGKQKCLEL QALLEEERRS
NSQLTEESTK QIQFLQTQLG KLQADMEALR EQRESTICST REELYSAQEE ILVLRHAMEA
ATAEREREIT VLQADLVSVR SELEHWRNTA AKYEEEIARL QEAFTQQEQQ QTAASELQGE
HCLHVCLSRG VIWCVCSTRE KSLVLSSSLE SLEKREEVLQ DKLGSLENQH LQDASRLKSQ
LDQAQAHTHT LQKEYEDTQS QLSDLRQRYE RTEQEKLNIH QELEQCRSSL KLLQDKSSSV
SAHTNTLCSF MIKNTDLCLD CFFVIYVCSA LSFTIIYFCF KVAFYAGEAA FLS
//
