ID A0A3P9CSP3_9CICH Unreviewed; 828 AA.
AC A0A3P9CSP3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Hemicentin-1 {ECO:0000313|Ensembl:ENSMZEP00005025375.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005025375.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005025375.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005025375.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P9CSP3; -.
DR Ensembl; ENSMZET00005026198.1; ENSMZEP00005025375.1; ENSMZEG00005018932.1.
DR GeneTree; ENSGT00940000159005; -.
DR Proteomes; UP000265160; LG4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005178; F:integrin binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 7.
DR InterPro; IPR047012; ICAM_VCAM.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR13771:SF19; CDNA, CLONE CSSL:D0139-RELATED; 1.
DR PANTHER; PTHR13771; INTERCELLULAR ADHESION MOLECULE; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13895; Ig_2; 1.
DR Pfam; PF13927; Ig_3; 1.
DR PIRSF; PIRSF000615; TyrPK_CSF1-R; 5.
DR SMART; SM00409; IG; 6.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 758..784
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 120..231
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 236..357
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 387..470
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 561..672
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 677..753
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 828 AA; 92303 MW; FB5CAC38051F9060 CRC64;
MTEGSLLSKA TQMSQSRLFV QLSVGLLLIA AGVGASCPIE LSPSSVVVRY GDPVSVNCTA
TVSHDGMGWE ASVGGIGITE VNHLPWNVES LTVWGISALC FINTNEQCQK NLNIVVYTFP
EKIQINSTAD SNGMMVEGEE YNITCEIPKI APVQNLTVKW YNGDRIIESD VLEIIEPNNL
KNTKQPVKLL STFPFTPTRN DSGARFRCEA QMDLSPVGPH LNVSSQELTI TVVFGPDVQC
SNIIELMENE SLEENCNIAG NPTPSVKWLK DGQPFNSTTP MRRENAGMYT LQANGSLSVQ
KNIQVHVLYG PELNCPSIYM AEEHTPHNLT CTVEGFPEPV MVWYRDDEVV ELPKTLTRLD
AGHYLITASN NQSNVNATVE IIVHYQPSEI FELQDLEVHI GSTVELKCSS SGNPRPTYTW
NYYQTDNVME ENEDGVSRLE IHSATAYNMG TYTCHAWNNK GRISRTIKVT VIGAEQECPL
EITPNPMVLE YRSRAQGATC SSTSAISTNV KRMYWEGVES DNMTWFTNTN EDWGMTPVCT
ATFQGIGKCQ KSLNFTLYKK PDSVSIYHVR RLSSVEEGKE FQLRCDIVSI APAQNVTVLW
YKNQDILKET GCQLENNKTC KLSDVRSPVN VSATINVNLQ RKDDEVVFRC EARLNLRLNP
LPTTTSSTLK ITVLYKPKIN TTKLPKEIPV FRGYPEELVC EADGNPTPKI KWGYNPESHV
NVSKGNLTVY GPGIYNCTAS NDVGSASYEV KVILKEDYLP LIAGFVAVTV VAISTIFIFI
YSIYYKNTKM RHYSLKNPKF SMHNGNVAHS NGDLQFPMTR LSKQYICI
//
