ID   A0A3P9D2H7_9CICH        Unreviewed;       785 AA.
AC   A0A3P9D2H7;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
OS   Maylandia zebra (zebra mbuna).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX   NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005028783.1, ECO:0000313|Proteomes:UP000265160};
RN   [1] {ECO:0000313|Ensembl:ENSMZEP00005028783.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3P9D2H7; -.
DR   Ensembl; ENSMZET00005029692.1; ENSMZEP00005028783.1; ENSMZEG00005021470.1.
DR   GeneTree; ENSGT01100000263487; -.
DR   Proteomes; UP000265160; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF13516; LRR_6; 2.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   SMART; SM01288; FISNA; 1.
DR   SMART; SM00368; LRR_RI; 5.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS51450; LRR; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265160}.
FT   DOMAIN          69..203
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   785 AA;  88261 MW;  81F639FFECD39401 CRC64;
     LSYKAKYIFR NTPYIYTELY ITEGGTAEVN DEHEVRQIET ASRKPDRPET TIRQEDIFKA
     SPGRDEPIRT VLTKGVAGIG KTVLTQKYSL DWAEDKANQD IQFIFPFTFR ELNVLKEEKF
     SLVGLVHHFF TETKEAGICS FEDFQVVFIF DGLDECRLPL DFHKTTILTD PRKSTSVDVL
     LINLIRGKLL PSARLWITTR PAAANQIPPD CVGMVTEVRG FTDPQKEEYF RKRFRDEEQA
     SRIISHIKTS RSLHIMCHIP VFCWITATVL EDVLETREGG QLPNTLTEMY IHFLVVQAKV
     KKVKYDGGAE TDPHWSSESR KMMESLGKLA FDQLQKGNLI FYESDLTECG IDIRAASVYS
     GVFTQIFKEE RGLYQDKVFC FIHLSVQEFL AALHVHLTFS NSGLNLLEEQ QRISMLSKLI
     SKPNLQSLHQ SAVNKALQSP NGHLDLFLRF LLGLSLQTNQ TLLRGLLTQT GSSSQTNQKT
     VQYIKKKLSK NLSAEKSINL FHCLNELNDR SLVEEIQQSL RSGRLSTGEL SPAQWSALVF
     ILLSSEEDLD VFDLKKYSAS EEALLRLLPV VKASNKALLS GCNLSERSCG ALSSVLNSQS
     SSLKELDLSN NDLRDSGVKL LSAALQSPHC TLETLRSVTC FSCYLITLQH KCFIFVIVYL
     LFFRLSNCDL SERSCEALSS GLSSQTSNLR QLDLSNINLK DSGVKLLSEG LKSPRCTLET
     LSLSGCLITE ESCTSLASAL SSNPSHLREL DLSYNHPGYS GMKLLSAGLN DPGWRLDTLR
     YGEKI
//