ID A0A3P9D3Z6_9CICH Unreviewed; 410 AA.
AC A0A3P9D3Z6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=WD repeat and SOCS box containing 2 {ECO:0000313|Ensembl:ENSMZEP00005029079.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005029079.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005029079.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3P9D3Z6; -.
DR Ensembl; ENSMZET00005029997.1; ENSMZEP00005029079.1; ENSMZEG00005021652.1.
DR GeneTree; ENSGT00940000159876; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000265160; Unplaced.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR15622:SF1; WD REPEAT AND SOCS BOX-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR15622; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00253; SOCS; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50225; SOCS; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265160};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 138..172
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 282..316
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 330..349
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 352..394
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 410 AA; 45669 MW; 9069E5EADCEC379F CRC64;
MVSTLEATSD PALLLELKTR RPPSLVERAG RETWSVDFSP DGAWFAWSMG HGIVWVVAWP
LDSEESQNGE TDRGDKSFSC GHPVWGLAFG PRPPKSNATA CPAKARSEGK NSLLLATGLE
NGVIKIWNVL TGSAVFDLHG HEGVVRDLVF PQNGTLTLIS SSRDKTLRIW DLAHKGKKVQ
VLYGHKDWIS SCCVSSDCSM IASMVCLWSL RSYTFIRNLT GGAHKTVYLL SSCDFSPDGA
ILATAAFSGS SWWIDLWDPY TAEKLYRSLN LDYFEDYGQN QISAIQFSPN GLHLTLVTDD
RALRIWELGE KGMVMETKRD RDSNGLCCKY HPQGGVVATG TRDGHVRFWR APSAVPSLCH
LCRSILRHSI STHQIEALPL PKRILEYLTY KNIPERLKSC CSSDEEEWES
//
