ID A0A3P9D5W0_9CICH Unreviewed; 634 AA.
AC A0A3P9D5W0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Carnitine O-acetyltransferase {ECO:0000313|Ensembl:ENSMZEP00005029734.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005029734.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005029734.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232}.
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DR RefSeq; XP_004573499.1; XM_004573442.2.
DR AlphaFoldDB; A0A3P9D5W0; -.
DR STRING; 106582.ENSMZEP00005029734; -.
DR Ensembl; ENSMZET00005030669.1; ENSMZEP00005029734.1; ENSMZEG00005022179.1.
DR GeneID; 101486106; -.
DR KEGG; mze:101486106; -.
DR GeneTree; ENSGT01060000248556; -.
DR OrthoDB; 3970920at2759; -.
DR Proteomes; UP000265160; Unplaced.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589:SF50; CARNITINE O-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR Pfam; PF00755; Carn_acyltransf; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 49..617
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT ACT_SITE 352
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
SQ SEQUENCE 634 AA; 71855 MW; DEC3772E63FD20E0 CRC64;
MLRIFSRIMV KLGKLNPPDQ VRSYQLVKPV RVILISDRYL NQQKGLPRVP VPPLRKTCEG
YLSALEPIIE EDEWKRAKQL VEAFMKRGGV GEELQRSLER KACNTDNWTT DLWGKLEYFG
NRSPVVINAN VPIACPRLDF RDKQGQIRCA AKLIIALLEF KTTIENETLP AENLGGKPLC
MEQYSQLLST CRIPGLERDS VVFHAKIGNP PKHITVAYNS QFFVVEVYHN DGTPLTVDQL
CVQMESICTS TSETNTEPVG ILTTLDRDSW SKAYLSMKDQ TNKESLSAIE RSIFTLCLDR
AIPRESDKYV TCDFHLITHG GGSQWNSANR WFDKSLQIIV AEDGSWGLNL IHIVADGTVS
MALTDYLVAS MKKPEMRQAS ILPLPMPQKL HFHVTPDIKE IIEQAKRSMD RNIQNFDLSV
LVFDHFGKNY LKAHNMSPDA FIQMAIQLAY YRMNKQVCAS YEAVSQRMFR RGRVSLLLST
TSVSAAFVKA FDDPQKQNTE KIDLLEKAIK THKENIKAVI GGHDIVAHII ALRLQAVENK
LPMPDIFRDI SYKKILNYQF AASQVTSNTG SVGVHQVDEN SGYSLCYSVH NSHFIIEMAT
SNTHKRLNTR HLIQNMKDAL LDMRALLEQA PRAT
//
