ID A0A3P9D5Z7_9CICH Unreviewed; 767 AA.
AC A0A3P9D5Z7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Melanocyte protein PMEL {ECO:0000313|Ensembl:ENSMZEP00005030003.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005030003.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005030003.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PMEL/NMB family.
CC {ECO:0000256|ARBA:ARBA00025776}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3P9D5Z7; -.
DR STRING; 106582.ENSMZEP00005030003; -.
DR Ensembl; ENSMZET00005030948.1; ENSMZEP00005030003.1; ENSMZEG00005022375.1.
DR GeneTree; ENSGT00950000183188; -.
DR OrthoDB; 5354575at2759; -.
DR Proteomes; UP000265160; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00146; PKD; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR045219; PKAT.
DR InterPro; IPR046846; PKAT_KLD.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR PANTHER; PTHR11861:SF1; MELANOCYTE PROTEIN PMEL; 1.
DR PANTHER; PTHR11861; MELANOCYTE PROTEIN PMEL 17-RELATED; 1.
DR Pfam; PF20433; PKAT_KLD; 1.
DR Pfam; PF00801; PKD; 1.
DR SMART; SM00089; PKD; 1.
DR SUPFAM; SSF49299; PKD domain; 1.
DR PROSITE; PS50093; PKD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..767
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017933514"
FT TRANSMEM 694..717
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 243..274
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT REGION 390..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 767 AA; 80190 MW; 096E533190012941 CRC64;
MKTLVLLVLA FATTISATRQ RSHFTRYRSW NSRMYPVWSD GDPRFRNCWL GGNVTFALKN
DAPTLTGAKA GFTINLNFPP NQTVLPGGEV VWANNCTVDG KQYEEGQAVY PDRDTDWTGV
FPDGTPFNRS QNGKPHYVFV WKTWGRYWQV ADGPSSSLTI GTDNIPLGSY NMEVVIYHCR
GRNRFIPLGY ASTVFTITDQ VPFTISLAQI NDVNQNDQNF IQNQAIGFTV NIHDPSQYLN
NAEISFTWDF GDNSGTLISR EHMVTHTYIE AGTFRPQVVL MASIPNNCGN PTAAGPVDAS
AAPAVVVMAS SQAAVPAVPV EGGDTIAVDV VATDATPVAA SVQPADANTD DGEAAADADT
EVVVVASVAP AAIDTAVVAA NTAAPAAEVE QEAADAEVPA ATVAPGAEEP ADADTAAADD
TAGVTVATED VAVIDAAAAS VAPVAEGEVE VADIITVAPI TDGATEEEAA DGVEAVEATA
AAEVALAETQ APADNVVAPA ATEPTAVEEA VVNAEVEAVE TENEVAATAA VEDEAAPAEG
EVQIEMEADP AQVALVVAKR QAPELTADCM VYRYGSLATS VDVVQGIESV EIVQVANVVS
LETALDQNAV DVTISCQGSL PSEVCTVISD ADCITPVQTI CNAASPSPDC QMILRQFFND
SGVFCLNVSL TNDVSLAMAS ARVSVSVASG GSPAGTAATV LGVMVLACVV CCIGLMYRRF
KQYQPLREDR ANNGGISAVT SVPLLLWNLL SRQSPGESRP LLQGRIV
//
