ID   A0A3P9D6E9_9CICH        Unreviewed;       894 AA.
AC   A0A3P9D6E9;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Protein NLRC3 {ECO:0000313|Ensembl:ENSMZEP00005029737.1};
OS   Maylandia zebra (zebra mbuna).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX   NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005029737.1, ECO:0000313|Proteomes:UP000265160};
RN   [1] {ECO:0000313|Ensembl:ENSMZEP00005029737.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P9D6E9; -.
DR   Ensembl; ENSMZET00005030672.1; ENSMZEP00005029737.1; ENSMZEG00005022171.1.
DR   GeneTree; ENSGT01100000263487; -.
DR   Proteomes; UP000265160; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   CDD; cd16040; SPRY_PRY_SNTX; 1.
DR   Gene3D; 2.60.120.920; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR006574; PRY.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF13516; LRR_6; 3.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   Pfam; PF13765; PRY; 1.
DR   SMART; SM01288; FISNA; 1.
DR   SMART; SM00368; LRR_RI; 3.
DR   SMART; SM00589; PRY; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265160}.
FT   DOMAIN          91..225
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   894 AA;  101338 MW;  370DA1EB7962C55E CRC64;
     MKQEKLAHEL KSNLKKKFQC VFEGIAKAGN PTLLNQIYTE LYITEGGTAE VNDVHEVRQI
     EKASRKPDSL EAIMRQEDVF KASPERDGTI RTVLTKGVAG IGKTVSTQKY TLDWAEDKAN
     QDIQFIFPFT FRELNVLKEE KFSLVELVHY FFKETKEAGI CSFEDFQVVF IFDGLDECRL
     PLDFHKTAIL TDPRKSTSVD VLLINLIRGK LLPSARLWIT TRPAAANQIP PGCFDMVTEV
     RGFTDPQKEE YFRKRFRDKK QAHRILSHIK TSRSLHIMCH IPVFCWITAT VLEDVLKTRE
     GGPLPKTLTE MYIHFLVVQA KVKKVKYDGG AETDPHWSPE SRKMIESLGK LAFDQLQNGK
     LIFYESDLTE CGIDIRAASV YSGVFTQIFK EERGLYRDKV FCFIHLSVQE FLAALHVHLT
     FIDSGLNLLE EQQTTSQKSE TRESAEKHFY QSAVDKALQS TNGHLDLFLR FLLGLSLQTN
     QTLLQGLLTL ARSSSQTNQK TVDYIKEKLS ENLSAEKSIN LFHCLNELND CSLVEEIQQS
     LRSGSLSADE LSPAQWSALV FILLSSEKDL DVFDLKKYSP SEEALFRLLP LVKASNKALL
     SGCNLLERSC EALSSVLSSM RMVDLSNNNL RDSGVKLLSV GLKSPHCTLE ALRLSGCLIT
     EEGCTSLTSA LSSNPSHLRE LDLSYNHPGP SGMKLLLAGL KDPSWRLDTL RVEPAGEQWL
     TPGLRKYSCQ LTIDTNTVHT NLQLSDNNSQ VTYVEEVQSY PDHPDRFDIC PQLLCRNGLT
     GCCYWEVEWR GNVRMSVSYR RTRRKGESPD CVFGWNDQSW SLWCSNYIPL SVYVDCPAGT
     LSFYRVSSDT LIHLHTFNTT FNETLYPGFT VWSGSSVTLC RFECKEHPPV RETV
//