ID A0A3P9D7G9_9CICH Unreviewed; 1487 AA.
AC A0A3P9D7G9;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=G-patch domain containing 8 {ECO:0000313|Ensembl:ENSMZEP00005030299.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005030299.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005030299.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005030299.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_004552302.1; XM_004552245.1.
DR STRING; 106582.ENSMZEP00005030299; -.
DR Ensembl; ENSMZET00005031252.1; ENSMZEP00005030299.1; ENSMZEG00005022584.1.
DR GeneID; 101469473; -.
DR KEGG; mze:101469473; -.
DR CTD; 23131; -.
DR GeneTree; ENSGT00940000159523; -.
DR OrthoDB; 2732746at2759; -.
DR Proteomes; UP000265160; LG4.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR17614:SF11; G PATCH DOMAIN-CONTAINING PROTEIN 8; 1.
DR PANTHER; PTHR17614; ZINC FINGER-CONTAINING; 1.
DR Pfam; PF01585; G-patch; 1.
DR SMART; SM00443; G_patch; 1.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR PROSITE; PS50174; G_PATCH; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 41..87
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT DOMAIN 137..166
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 201..241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 253..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 316..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 425..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 566..1095
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1116..1195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 92..133
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..19
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 441..466
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 577..593
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 605..624
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 635..657
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 658..676
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 690..712
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 773..806
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 822..841
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 842..856
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 857..888
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 889..912
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 937..953
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 954..989
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 991..1012
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1013..1039
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1047..1061
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1119..1133
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1146..1162
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1165..1185
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1487 AA; 163033 MW; 836EADA58EFB6FAB CRC64;
MADRFSRFNE ERDFQGGNHF DQYEEGQLEL EQASLDKPIE SDNIGHRLLQ KHGWKLGQGL
GKTMQGRTDP VPIILKYDVM GMGRMEMELD YAEDATEKRR VLEVEKEDTE ELRQKYKDQM
EKEKAIAKAL EDLRANFYCE LCDKQYTKHQ EFDNHINSYD HAHKQRLKEL KQREFARNVS
SRSRKDGKKQ EKMLRRLHEL AEQRKQQDRT PGSGPMFKTT TVAVDGEKGE DSNSMTPENS
MTQSLADTAL EGSLSDKTGQ ASPKSGPTFS FSLGKNASSS PTSSNASKVS VSFSFAKKAP
VKLETAAAVF ADHGEEAMET EESQEGEKAG GQDDTSGCGT DSPKGLSGGG EGGEGADAAG
TEEVQQPDDG GSLASTLSKL KMMMKTNEGY VGQEPQYYHY VPPAHCRVKP HFQFLLFMKA
SEQCQSKDED DEEETQEENK AEESPEQTES GVTECKTEKE HGNVTVDADP DLVPLSANVK
AEEETPSCAE DAAPAVPASP TQKGETRDTV DTNAGPKMPT GPFFPVLSKD ETTTLQWPSE
LLEFTKAQPS LSYSCNPLYF DFKLSRNKGV RGGKVAKSPK PGEDTDDKGQ EVNASPSEVE
MATKPGTSAD KDKLVSKGES GQPESEEQKP TSGSNSAKKK KKKKKHKKSA KHSKRKGKEK
GAREDAEGET EVTQEKPKKK KKHKRKKSKN KAQDQAEATG EEKEKPKPKS EDKAATSSVQ
LTTGGEGATG AELGKRKRGA KEVPCKSGAE GGNGKSTDKA NSSEEHSGNK RQKTDTSASQ
SASCSTSAQK SPGSGRPPSS ESEEGGSNTQ RSRHHRSSPR EQRRHHSEES GRSCSRSSRR
GERRGSSRRR HRGQTSRSRS YSSSSERSSA GSSAYSHRSR SYSDSYSDYS TEGRRRRRSK
RSSDSEYDRR SSRGRRRSRR HQYTSSSSED SRSRSRSYSR RKRHRRHHRS SSRSSSSWSR
STSARSWRRS YSRSYSSASR SSSSNKGSPH RRSTRGREDS DTHRRDFNRS RIYRSQSPRS
SSSRGLNRNT HSSSSLGLRP GGSRDAGEQK NTLTARQLLE KVQSKKSSED STTGTKSGIK
IKDPPQGYFG PKLPPSLGNK AMLPLIGKLQ AGKKPAIPLI RPEEGEKSGT GKSSEPEGEV
ILVEPIREFP PPPPPPAPPV QKVEEAPQST VTQEETQQPA TEDQGHQETR PVFEQEPSMM
MPQYQGESGQ DLSQNQMMES MMPEMQQQQA AMHAYPGYPP PSLEEDGMEA EEDGLAPLES
QPITFTPEEM EKYSKLQQAA QQHIQQQLLA KQVKTFPSAA AAAAAAAAAT LAPAPPPPAL
QQIHIQQPTV SVASGTSITT VQHAILQHHA ATAAAMGIHP AHPHHPHPAH AQLAQVHHIP
QHHLTPISLS PLGPSLGHSL GHSLGHAGLI PAHPTAFLSG QPIHIIPASA LHHTPLALHH
VPHTALYPTL FTPRPSQAAA AAALQLHPLL HPIFSGQDLQ HPPNHGS
//
