ID A0A3P9D814_9CICH Unreviewed; 744 AA.
AC A0A3P9D814;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=UV radiation resistance associated {ECO:0000313|Ensembl:ENSMZEP00005030835.1};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005030835.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005030835.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005030835.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_004561682.1; XM_004561625.1.
DR AlphaFoldDB; A0A3P9D814; -.
DR STRING; 106582.ENSMZEP00005030835; -.
DR Ensembl; ENSMZET00005031814.1; ENSMZEP00005030835.1; ENSMZEG00005022971.1.
DR GeneID; 101484718; -.
DR KEGG; mze:101484718; -.
DR CTD; 7405; -.
DR GeneTree; ENSGT00390000012877; -.
DR OrthoDB; 5481315at2759; -.
DR Proteomes; UP000265160; LG10.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0032991; C:protein-containing complex; IEA:UniProt.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR018791; UV_resistance/autophagy_Atg14.
DR PANTHER; PTHR15157; UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN; 1.
DR PANTHER; PTHR15157:SF5; UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN; 1.
DR Pfam; PF10186; ATG14; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160}.
FT REGION 488..638
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 265..302
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 520..536
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 545..565
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 566..608
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 609..626
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 744 AA; 83671 MW; D88A58C49E93538C CRC64;
MNSITGRVLA IPAASVTNSG ASASRALHVE LTSQQRRLRH LRSIAARNIV NRNGSPLLDT
YFTLHLCIGD RISRDFYKSE VIRDSLNPTW RSLDFGMLPD LLDTSVSCFV VRIWGGQKEQ
YQLLIEWKVN LDGLRYTGQQ IRSRNPNEII FGLNDGYYAA DFDQKDQSER KKNSLLQVDQ
SSVRNSYSVF SLLRLHTAQR AIKQTQVTVQ KIGKEIEEKL RTTAACTERK KERECMQLRI
AVLHSELERQ RKALGRERDL RQKERALLQK KEDSFSAQHE RLKEEKESLS KLQKECTAKR
EQFLKSNAQL TFRCRQLLSE LSYIYPIDVT NQSDYVICGV KLPNSEDFQA KDDGSIAVAL
GYTAHLVLMI SCFLQIPLRY PVIHKGSRSS IKDTITDRLT EKEREFPLYP RGERFHFEYG
VYLLNKNIAQ LRYQHGLTTP DLQQTLPNLK NFLEHGLMVR CDRHHVSSSI PVPAKSQLGV
SAASELAYPC HTSSPDRGLR NRASSEAEAE LKYKPATPPP SYNTAISEGK SQVGLGPPSP
SPSPTHLSSS LDPSKAPLDL STNTETIVEE EQKEEKQEAR GTAVEAEGRE TAEGESERHK
ENKSDEMEEN PSSSSMIPNS SAVQDADEET MPAAQHPGAM NGSLVLEQAP ISLIPELRCS
VEQAEEIMGT EATGLGLGMG LGLADEARLD DYRCIPVDHA VAVECDEQVL GELDMAGFEE
FSRRIYALNE NMSSFRRPRK NSEK
//
