ID   A0A3P9DJ91_9CICH        Unreviewed;       520 AA.
AC   A0A3P9DJ91;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=AIG1-type G domain-containing protein {ECO:0000259|Pfam:PF04548};
OS   Maylandia zebra (zebra mbuna).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX   NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005034830.1, ECO:0000313|Proteomes:UP000265160};
RN   [1] {ECO:0000313|Ensembl:ENSMZEP00005034830.1, ECO:0000313|Proteomes:UP000265160}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=25186727; DOI=10.1038/nature13726;
RA   Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA   Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA   Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA   Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA   Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA   Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA   Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA   Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA   Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA   Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA   Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA   Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA   Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA   Di Palma F.;
RT   "The genomic substrate for adaptive radiation in African cichlid fish.";
RL   Nature 513:375-381(2014).
RN   [2] {ECO:0000313|Ensembl:ENSMZEP00005034830.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC       GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC       IAN subfamily. {ECO:0000256|ARBA:ARBA00008535}.
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DR   AlphaFoldDB; A0A3P9DJ91; -.
DR   Ensembl; ENSMZET00005036070.1; ENSMZEP00005034830.1; ENSMZEG00005026042.1.
DR   GeneTree; ENSGT00500000044904; -.
DR   Proteomes; UP000265160; LG22.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR006703; G_AIG1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR   PANTHER; PTHR32046; G DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR32046:SF14; IMMUNE-ASSOCIATED NUCLEOTIDE-BINDING PROTEIN 10-LIKE; 1.
DR   Pfam; PF04548; AIG1; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265160}.
FT   DOMAIN          49..205
FT                   /note="AIG1-type G"
FT                   /evidence="ECO:0000259|Pfam:PF04548"
FT   REGION          495..520
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          279..323
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          415..452
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   520 AA;  59498 MW;  426AF10A69A6DB3E CRC64;
     GDSRLFTNWV VSGSFPGWPK LFSTLHFTRK FGSLTRMTVG EKNQNKPNKT ILLVGETGAG
     KSTLINALVN FTMGVQFEDG VWFQIIEEEK RSQTSDVIVY EIFGFEDKSL PYSLTIIDTP
     GFGDTTSTKR DESISERLLD LFQSEDGVNK IHAVGLVMKA SEIRLSDRQM YILDSVASLF
     GKDLEKSIVA LITHSDGVTP ENALKALEIA KIECPRNGNN EPVHFLFNNQ QSKERTEKNE
     SCLETAWRIT ERGMDELTAF LGKTAPEKLL VTTKVLRERI KLNACIENLK ERINEVELKQ
     TEARQIQEEL EKHKEEMQNN EKFSVEVLEF YKDKEYVKTG WWGGVFYNGT LCCTNCQENC
     HLDCTMAWYP GQCDVMSGGY CTSCTGKCRA SDHVKGNWRY VLKTRKVWQT SEDMKKKYEK
     NKSESQKQMS LLEHLQGEIS QLAAEKSQLL GESYQRLVTL EEIALKADSA STFVRLDFLI
     EKMKEEQNTE KVQKLEEMRK RVDEGTRPGS RYMQGKKLEK
//